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6fws

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Current revision (12:31, 9 May 2024) (edit) (undo)
 
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==Structure of DinG in complex with ssDNA and ADPBeF==
==Structure of DinG in complex with ssDNA and ADPBeF==
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<StructureSection load='6fws' size='340' side='right' caption='[[6fws]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='6fws' size='340' side='right'caption='[[6fws]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6fws]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FWS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FWS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6fws]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FWS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FWS FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fws OCA], [http://pdbe.org/6fws PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fws RCSB], [http://www.ebi.ac.uk/pdbsum/6fws PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fws ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6fws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fws OCA], [https://pdbe.org/6fws PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6fws RCSB], [https://www.ebi.ac.uk/pdbsum/6fws PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6fws ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A0A2H4TNL0_ECOLX A0A2H4TNL0_ECOLX]] DNA-dependent ATPase and 5'-3' DNA helicase.[HAMAP-Rule:MF_02205]
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[https://www.uniprot.org/uniprot/DING_ECOLI DING_ECOLI] DNA-dependent ATPase and 5'-3' DNA helicase (PubMed:12748189, PubMed:17416902). Can also unwind DNA-RNA hybrid duplexes. Is active on D-loops and R-loops, and on forked structures (PubMed:17416902). May be involved in recombinational DNA repair and the resumption of replication after DNA damage (PubMed:17416902). The redox cluster is involved in DNA-mediated charge-transport signaling between DNA repair proteins from distinct pathways. DinG cooperates at long-range with endonuclease III, a base excision repair enzyme, using DNA charge transport to redistribute to regions of DNA damage (PubMed:24738733).<ref>PMID:12748189</ref> <ref>PMID:17416902</ref> <ref>PMID:24738733</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6fws" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6fws" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Helicase 3D structures|Helicase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cheng, K]]
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[[Category: Escherichia coli]]
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[[Category: Wigley, D]]
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[[Category: Large Structures]]
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[[Category: Atp]]
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[[Category: Synthetic construct]]
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[[Category: Dna binding]]
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[[Category: Cheng K]]
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[[Category: Dna binding protein]]
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[[Category: Wigley D]]
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[[Category: Helicase]]
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[[Category: Translocase]]
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Current revision

Structure of DinG in complex with ssDNA and ADPBeF

PDB ID 6fws

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