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| | ==Structure of cold shock protein E from Salmonella typhimurium== | | ==Structure of cold shock protein E from Salmonella typhimurium== |
| - | <StructureSection load='3i2z' size='340' side='right' caption='[[3i2z]], [[Resolution|resolution]] 1.10Å' scene=''> | + | <StructureSection load='3i2z' size='340' side='right'caption='[[3i2z]], [[Resolution|resolution]] 1.10Å' scene=''> |
| | == Structural highlights == | | == Structural highlights == |
| - | <table><tr><td colspan='2'>[[3i2z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I2Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I2Z FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[3i2z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I2Z FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mjc|1mjc]], [[1csp|1csp]], [[1c9o|1c9o]], [[2es2|2es2]], [[2hax|2hax]]</td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1Å</td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cold shock protein E, cspE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=90371 "Bacillus typhimurium" Loeffler 1892])</td></tr>
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i2z OCA], [https://pdbe.org/3i2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i2z RCSB], [https://www.ebi.ac.uk/pdbsum/3i2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i2z ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i2z OCA], [http://pdbe.org/3i2z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3i2z RCSB], [http://www.ebi.ac.uk/pdbsum/3i2z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3i2z ProSAT]</span></td></tr> | + | |
| | </table> | | </table> |
| | + | == Function == |
| | + | [https://www.uniprot.org/uniprot/Q7CQZ5_SALTY Q7CQZ5_SALTY] |
| | == Evolutionary Conservation == | | == Evolutionary Conservation == |
| | [[Image:Consurf_key_small.gif|200px|right]] | | [[Image:Consurf_key_small.gif|200px|right]] |
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| | __TOC__ | | __TOC__ |
| | </StructureSection> | | </StructureSection> |
| - | [[Category: Bacillus typhimurium loeffler 1892]] | + | [[Category: Large Structures]] |
| - | [[Category: Gallagher, M]] | + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium]] |
| - | [[Category: McNae, I]] | + | [[Category: Gallagher M]] |
| - | [[Category: Morgan, H P]]
| + | [[Category: McNae I]] |
| - | [[Category: Walkinshaw, M D]]
| + | [[Category: Morgan HP]] |
| - | [[Category: Wear, M A]] | + | [[Category: Walkinshaw MD]] |
| - | [[Category: Beta barrel]] | + | [[Category: Wear MA]] |
| - | [[Category: Cytoplasm]] | + | |
| - | [[Category: Dna binding protein/transcription]] | + | |
| - | [[Category: Gene regulation]]
| + | |
| Structural highlights
Function
Q7CQZ5_SALTY
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
In prokaryotic organisms, cold shock triggers the production of a small highly conserved family of cold-shock proteins (CSPs). CSPs have been well studied structurally and functionally in Escherichia coli and Bacillus subtilis, but Salmonella typhimurium CSPs remain relatively uncharacterized. In S. typhimurium, six homologous CSPs have been identified: StCspA-E and StCspH. The crystal structure of cold-shock protein E from S. typhimurium (StCspE) has been determined at 1.1 A resolution and has an R factor of 0.203 after refinement. The three-dimensional structure is similar to those of previously determined CSPs and is composed of five antiparallel beta-strands forming a classic OB fold/five-stranded beta-barrel. This first structure of a CSP from S. typhimurium provides new insight into the cold-shock response of this bacterium.
Crystallization and X-ray structure of cold-shock protein E from Salmonella typhimurium.,Morgan HP, Wear MA, McNae I, Gallagher MP, Walkinshaw MD Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Dec 1;65(Pt, 12):1240-5. Epub 2009 Nov 27. PMID:20054119[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Morgan HP, Wear MA, McNae I, Gallagher MP, Walkinshaw MD. Crystallization and X-ray structure of cold-shock protein E from Salmonella typhimurium. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Dec 1;65(Pt, 12):1240-5. Epub 2009 Nov 27. PMID:20054119 doi:10.1107/S1744309109033788
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