3c0c

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[[Image:3c0c.jpg|left|200px]]
 
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{{Structure
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==X-ray Crystal Structure of the Rat Endophilin A2 SH3 Domain==
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|PDB= 3c0c |SIZE=350|CAPTION= <scene name='initialview01'>3c0c</scene>, resolution 1.700&Aring;
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<StructureSection load='3c0c' size='340' side='right'caption='[[3c0c]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
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<table><tr><td colspan='2'>[[3c0c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C0C FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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|GENE= Sh3gl1, Sh3p8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c0c OCA], [https://pdbe.org/3c0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c0c RCSB], [https://www.ebi.ac.uk/pdbsum/3c0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c0c ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c0c OCA], [http://www.ebi.ac.uk/pdbsum/3c0c PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3c0c RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/SH3G1_RAT SH3G1_RAT] Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).
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== Evolutionary Conservation ==
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'''X-ray Crystal Structure of the Rat Endophilin A2 SH3 Domain'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c0/3c0c_consurf.spt"</scriptWhenChecked>
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3C0C is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C0C OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c0c ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Single protein]]
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[[Category: Loll PJ]]
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[[Category: Loll, P J.]]
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[[Category: Swain E]]
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[[Category: Swain, E.]]
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[[Category: chromosomal rearrangement]]
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[[Category: coiled coil]]
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[[Category: cytoplasm]]
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[[Category: endocytosis]]
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[[Category: endosome]]
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[[Category: lipid-binding]]
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[[Category: membrane]]
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[[Category: phosphoprotein]]
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[[Category: proto-oncogene]]
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[[Category: sh3]]
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[[Category: sh3 domain]]
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[[Category: voltage-gated calcium channel]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:29:54 2008''
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Current revision

X-ray Crystal Structure of the Rat Endophilin A2 SH3 Domain

PDB ID 3c0c

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