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3c5i

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[[Image:3c5i.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of Plasmodium knowlesi choline kinase, PKH_134520==
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|PDB= 3c5i |SIZE=350|CAPTION= <scene name='initialview01'>3c5i</scene>, resolution 2.200&Aring;
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<StructureSection load='3c5i' size='340' side='right'caption='[[3c5i]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:Mg+Binding+Site+For+Residue+A+370'>AC1</scene>, <scene name='pdbsite=AC2:Mg+Binding+Site+For+Residue+B+370'>AC2</scene>, <scene name='pdbsite=AC3:Mg+Binding+Site+For+Residue+C+370'>AC3</scene>, <scene name='pdbsite=AC4:Mg+Binding+Site+For+Residue+D+370'>AC4</scene>, <scene name='pdbsite=AC5:Ca+Binding+Site+For+Residue+A+371'>AC5</scene>, <scene name='pdbsite=AC6:Ca+Binding+Site+For+Residue+B+371'>AC6</scene>, <scene name='pdbsite=AC7:Ca+Binding+Site+For+Residue+C+371'>AC7</scene>, <scene name='pdbsite=AC8:Ca+Binding+Site+For+Residue+D+371'>AC8</scene>, <scene name='pdbsite=AC9:Cht+Binding+Site+For+Residue+A+1001'>AC9</scene>, <scene name='pdbsite=BC1:Cht+Binding+Site+For+Residue+B+1001'>BC1</scene>, <scene name='pdbsite=BC2:Unl+Binding+Site+For+Residue+D+372'>BC2</scene>, <scene name='pdbsite=BC3:Gol+Binding+Site+For+Residue+A+1002'>BC3</scene>, <scene name='pdbsite=BC4:Gol+Binding+Site+For+Residue+B+1003'>BC4</scene>, <scene name='pdbsite=BC5:Gol+Binding+Site+For+Residue+A+1003'>BC5</scene>, <scene name='pdbsite=BC6:Gol+Binding+Site+For+Residue+C+373'>BC6</scene>, <scene name='pdbsite=BC7:Gol+Binding+Site+For+Residue+D+373'>BC7</scene>, <scene name='pdbsite=BC8:Gol+Binding+Site+For+Residue+C+374'>BC8</scene>, <scene name='pdbsite=BC9:Gol+Binding+Site+For+Residue+B+1004'>BC9</scene>, <scene name='pdbsite=CC1:Gol+Binding+Site+For+Residue+C+375'>CC1</scene>, <scene name='pdbsite=CC2:Gol+Binding+Site+For+Residue+D+374'>CC2</scene> and <scene name='pdbsite=CC3:Gol+Binding+Site+For+Residue+D+375'>CC3</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CHT:CHOLINE+ION'>CHT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene>
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<table><tr><td colspan='2'>[[3c5i]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_knowlesi Plasmodium knowlesi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C5I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C5I FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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|GENE= PKH_134520 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5850 Plasmodium knowlesi])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CHT:CHOLINE+ION'>CHT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c5i OCA], [https://pdbe.org/3c5i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c5i RCSB], [https://www.ebi.ac.uk/pdbsum/3c5i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c5i ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c5i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c5i OCA], [http://www.ebi.ac.uk/pdbsum/3c5i PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3c5i RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/D0VWT1_PLAKN D0VWT1_PLAKN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c5/3c5i_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c5i ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of Plasmodium knowlesi choline kinase, PKH_134520'''
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==See Also==
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*[[Choline kinase 3D structures|Choline kinase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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3C5I is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Plasmodium_knowlesi Plasmodium knowlesi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C5I OCA].
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[[Category: Large Structures]]
[[Category: Plasmodium knowlesi]]
[[Category: Plasmodium knowlesi]]
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[[Category: Protein complex]]
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[[Category: Arrowsmith CH]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Artz JD]]
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[[Category: Artz, J D.]]
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[[Category: Bochkarev A]]
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[[Category: Bochkarev, A.]]
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[[Category: Bountra C]]
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[[Category: Bountra, C.]]
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[[Category: Cossar D]]
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[[Category: Cossar, D.]]
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[[Category: Edwards AM]]
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[[Category: Edwards, A M.]]
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[[Category: Hills T]]
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[[Category: Hills, T.]]
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[[Category: Hui R]]
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[[Category: Hui, R.]]
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[[Category: Kozieradzki I]]
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[[Category: Kozieradzki, I.]]
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[[Category: Lew J]]
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[[Category: Lew, J.]]
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[[Category: Schapira M]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Senesterra G]]
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[[Category: Schapira, M.]]
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[[Category: Vedadi M]]
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[[Category: Senesterra, G.]]
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[[Category: Wasney G]]
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[[Category: Vedadi, M.]]
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[[Category: Weigelt J]]
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[[Category: Wasney, G.]]
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[[Category: Wernimont AK]]
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[[Category: Weigelt, J.]]
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[[Category: Xiao T]]
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[[Category: Wernimont, A K.]]
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[[Category: Xiao, T.]]
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[[Category: choline]]
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[[Category: kinase]]
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[[Category: malaria]]
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[[Category: plasmodium knowlesi]]
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[[Category: sgc]]
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[[Category: structural genomic]]
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[[Category: structural genomics consortium]]
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[[Category: transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:30:44 2008''
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Current revision

Crystal structure of Plasmodium knowlesi choline kinase, PKH_134520

PDB ID 3c5i

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