6iz7
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6iz7 is ON HOLD Authors: Sengupta, J., Bhakta, S., Akbar, S. Description: E. coli methionine aminopeptidase crystal structure fitted into the cryo-...) |
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- | '''Unreleased structure''' | ||
- | + | ==E. coli methionine aminopeptidase crystal structure fitted into the cryo-EM density map of E. coli 70S ribosome in complex with methionine aminopeptidase== | |
+ | <SX load='6iz7' size='340' side='right' viewer='molstar' caption='[[6iz7]], [[Resolution|resolution]] 11.80Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[6iz7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IZ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IZ7 FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 11.8Å</td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6iz7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iz7 OCA], [https://pdbe.org/6iz7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6iz7 RCSB], [https://www.ebi.ac.uk/pdbsum/6iz7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6iz7 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/MAP1_ECOLI MAP1_ECOLI] Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.[HAMAP-Rule:MF_01974]<ref>PMID:20521764</ref> <ref>PMID:3027045</ref> | ||
- | + | ==See Also== | |
- | + | *[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]] | |
- | + | == References == | |
- | [[Category: | + | <references/> |
- | [[Category: | + | __TOC__ |
- | [[Category: | + | </SX> |
- | [[Category: | + | [[Category: Escherichia coli K-12]] |
+ | [[Category: Large Structures]] | ||
+ | [[Category: Akbar S]] | ||
+ | [[Category: Bhakta S]] | ||
+ | [[Category: Sengupta J]] |
Current revision
E. coli methionine aminopeptidase crystal structure fitted into the cryo-EM density map of E. coli 70S ribosome in complex with methionine aminopeptidase
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