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3c8w

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[[Image:3c8w.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of acetoacetate decarboxylase (ADC) (YP_094708.1) from Legionella pneumophila subsp. pneumophila str. Philadelphia 1 at 1.60 A resolution==
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|PDB= 3c8w |SIZE=350|CAPTION= <scene name='initialview01'>3c8w</scene>, resolution 1.600&Aring;
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<StructureSection load='3c8w' size='340' side='right'caption='[[3c8w]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:Cit+Binding+Site+For+Residue+D+255'>AC1</scene>, <scene name='pdbsite=AC2:Cit+Binding+Site+For+Residue+A+255'>AC2</scene>, <scene name='pdbsite=AC3:Cit+Binding+Site+For+Residue+B+255'>AC3</scene> and <scene name='pdbsite=AC4:Cit+Binding+Site+For+Residue+C+255'>AC4</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=LCK:(Z)-N~6~-(2-CARBOXY-1-METHYLETHYLIDENE)-L-LYSINE'>LCK</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
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<table><tr><td colspan='2'>[[3c8w]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_str._Philadelphia_1 Legionella pneumophila subsp. pneumophila str. Philadelphia 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C8W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C8W FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetoacetate_decarboxylase Acetoacetate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.4 4.1.1.4] </span>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=LCK:(Z)-N~6~-(2-CARBOXY-1-METHYLETHYLIDENE)-L-LYSINE'>LCK</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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|GENE= YP_094708.1, lpg0672 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272624 Legionella pneumophila subsp. pneumophila str. Philadelphia 1])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c8w OCA], [https://pdbe.org/3c8w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c8w RCSB], [https://www.ebi.ac.uk/pdbsum/3c8w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c8w ProSAT], [https://www.topsan.org/Proteins/JCSG/3c8w TOPSAN]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c8w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c8w OCA], [http://www.ebi.ac.uk/pdbsum/3c8w PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3c8w RCSB]</span>
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[https://www.uniprot.org/uniprot/Q5ZXQ9_LEGPH Q5ZXQ9_LEGPH]
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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'''Crystal structure of acetoacetate decarboxylase (ADC) (YP_094708.1) from Legionella pneumophila subsp. pneumophila str. Philadelphia 1 at 1.60 A resolution'''
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c8/3c8w_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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3C8W is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Legionella_pneumophila_subsp._pneumophila_str._philadelphia_1 Legionella pneumophila subsp. pneumophila str. philadelphia 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C8W OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Acetoacetate decarboxylase]]
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</jmolCheckbox>
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[[Category: Legionella pneumophila subsp. pneumophila str. philadelphia 1]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c8w ConSurf].
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[[Category: Single protein]]
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<div style="clear:both"></div>
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[[Category: JCSG, Joint Center for Structural Genomics.]]
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__TOC__
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[[Category: acetoacetate decarboxylase (adc)]]
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</StructureSection>
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[[Category: jcsg]]
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[[Category: Large Structures]]
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[[Category: joint center for structural genomic]]
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[[Category: Legionella pneumophila subsp. pneumophila str. Philadelphia 1]]
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[[Category: lyase]]
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[[Category: protein structure initiative]]
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[[Category: psi-2]]
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[[Category: structural genomic]]
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[[Category: yp_094708 1]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:31:09 2008''
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Current revision

Crystal structure of acetoacetate decarboxylase (ADC) (YP_094708.1) from Legionella pneumophila subsp. pneumophila str. Philadelphia 1 at 1.60 A resolution

PDB ID 3c8w

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