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6ne3
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6ne3 is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of singly-bound SNF2h-nucleosome complex with SNF2h bound at SHL-2== | |
| + | <SX load='6ne3' size='340' side='right' viewer='molstar' caption='[[6ne3]], [[Resolution|resolution]] 3.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6ne3]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6NE3 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.9Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ne3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ne3 OCA], [https://pdbe.org/6ne3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ne3 RCSB], [https://www.ebi.ac.uk/pdbsum/6ne3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ne3 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||
| - | + | ==See Also== | |
| - | + | *[[Histone 3D structures|Histone 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </SX> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Xenopus laevis]] | ||
| + | [[Category: Armache J-P]] | ||
| + | [[Category: Cheng Y]] | ||
| + | [[Category: Gamarra N]] | ||
| + | [[Category: Johnson SL]] | ||
| + | [[Category: Leonard JD]] | ||
| + | [[Category: Narlikar GN]] | ||
| + | [[Category: Wu S]] | ||
Current revision
Cryo-EM structure of singly-bound SNF2h-nucleosome complex with SNF2h bound at SHL-2
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Categories: Homo sapiens | Large Structures | Xenopus laevis | Armache J-P | Cheng Y | Gamarra N | Johnson SL | Leonard JD | Narlikar GN | Wu S
