3c96

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[[Image:3c96.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa. Northeast Structural Genomics Consortium target PaR240==
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|PDB= 3c96 |SIZE=350|CAPTION= <scene name='initialview01'>3c96</scene>, resolution 1.90&Aring;
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<StructureSection load='3c96' size='340' side='right'caption='[[3c96]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:Fad+Binding+Site+For+Residue+A+501'>AC1</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>
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<table><tr><td colspan='2'>[[3c96]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3C96 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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|GENE= phzS, PA4217 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 Pseudomonas aeruginosa PAO1])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
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|DOMAIN=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3c96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c96 OCA], [https://pdbe.org/3c96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3c96 RCSB], [https://www.ebi.ac.uk/pdbsum/3c96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3c96 ProSAT], [https://www.topsan.org/Proteins/NESGC/3c96 TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3c96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3c96 OCA], [http://www.ebi.ac.uk/pdbsum/3c96 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3c96 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/PHZS_PSEAE PHZS_PSEAE] Involved in the biosynthesis of pyocyanine, a blue-pigmented phenazine derivative, which plays a role in virulence. Catalyzes the oxidative decarboxylation of 5-methylphenazine-1-carboxylate (5-methyl-PCA) to pyocyanine. Can also act on phenazine-1-carboxylate (PCA), converting it into 1-hydroxyphenazine (1-HP). However, PCA is a poor substrate.<ref>PMID:17253782</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c9/3c96_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3c96 ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa. Northeast Structural Genomics Consortium target PaR240'''
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==See Also==
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*[[Monooxygenase 3D structures|Monooxygenase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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3C96 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C96 OCA].
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__TOC__
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[[Category: Pseudomonas aeruginosa pao1]]
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</StructureSection>
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Acton, T B.]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Chen, Y.]]
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[[Category: Acton TB]]
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[[Category: Hunt, J F.]]
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[[Category: Chen Y]]
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[[Category: Mao, L.]]
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[[Category: Hunt JF]]
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[[Category: Montelione, G T.]]
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[[Category: Mao L]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Montelione GT]]
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[[Category: Seetharaman, J.]]
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[[Category: Seetharaman J]]
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[[Category: Tong, L.]]
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[[Category: Tong L]]
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[[Category: Vorobiev, S M.]]
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[[Category: Vorobiev SM]]
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[[Category: Wang, D.]]
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[[Category: Wang D]]
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[[Category: Xiao, R.]]
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[[Category: Xiao R]]
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[[Category: fad]]
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[[Category: monooxygenase]]
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[[Category: nesg]]
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[[Category: northeast structural genomics consortium]]
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[[Category: oxidoreductase]]
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[[Category: par240]]
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[[Category: pf01266]]
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[[Category: protein structure initiative]]
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[[Category: psi-2]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:31:08 2008''
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Current revision

Crystal structure of the flavin-containing monooxygenase phzS from Pseudomonas aeruginosa. Northeast Structural Genomics Consortium target PaR240

PDB ID 3c96

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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