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6a9x

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==Crystal Structure of AnkG/GABARAP Complex==
==Crystal Structure of AnkG/GABARAP Complex==
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<StructureSection load='6a9x' size='340' side='right' caption='[[6a9x]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='6a9x' size='340' side='right'caption='[[6a9x]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6a9x]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A9X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6A9X FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6a9x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A9X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6A9X FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6a9x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a9x OCA], [http://pdbe.org/6a9x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6a9x RCSB], [http://www.ebi.ac.uk/pdbsum/6a9x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6a9x ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.202&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6a9x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a9x OCA], [https://pdbe.org/6a9x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6a9x RCSB], [https://www.ebi.ac.uk/pdbsum/6a9x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6a9x ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GBRAP_MOUSE GBRAP_MOUSE]] Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity). [[http://www.uniprot.org/uniprot/ANK3_RAT ANK3_RAT]] Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments. In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Regulates KCNA1 channel activity in function of dietary Mg(2+) levels, and thereby contributes to the regulation of renal Mg(2+) reabsorption (By similarity).[UniProtKB:G5E8K5]
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[https://www.uniprot.org/uniprot/GBRAP_MOUSE GBRAP_MOUSE] Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6a9x" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6a9x" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Ankyrin 3D structures|Ankyrin 3D structures]]
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*[[GABA receptor-associated protein 3D structures|GABA receptor-associated protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Chen, K]]
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[[Category: Large Structures]]
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[[Category: Li, J]]
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[[Category: Mus musculus]]
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[[Category: Wang, C]]
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[[Category: Rattus norvegicus]]
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[[Category: Zhang, M]]
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[[Category: Chen K]]
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[[Category: Protein binding]]
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[[Category: Li J]]
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[[Category: Signaling protein]]
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[[Category: Wang C]]
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[[Category: Structural protein]]
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[[Category: Zhang M]]

Current revision

Crystal Structure of AnkG/GABARAP Complex

PDB ID 6a9x

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