1mdx

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==Crystal structure of ArnB transferase with pyridoxal 5' phosphate==
==Crystal structure of ArnB transferase with pyridoxal 5' phosphate==
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<StructureSection load='1mdx' size='340' side='right' caption='[[1mdx]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
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<StructureSection load='1mdx' size='340' side='right'caption='[[1mdx]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1mdx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_typhimurium"_loeffler_1892 "bacillus typhimurium" loeffler 1892]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MDX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MDX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1mdx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MDX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MDX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mdo|1mdo]], [[1mdz|1mdz]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AKG:2-OXOGLUTARIC+ACID'>AKG</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mdx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mdx OCA], [http://pdbe.org/1mdx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1mdx RCSB], [http://www.ebi.ac.uk/pdbsum/1mdx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1mdx ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mdx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mdx OCA], [https://pdbe.org/1mdx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mdx RCSB], [https://www.ebi.ac.uk/pdbsum/1mdx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mdx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ARNB_SALTY ARNB_SALTY]] Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity).[HAMAP-Rule:MF_01167]
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[https://www.uniprot.org/uniprot/ARNB_SALTY ARNB_SALTY] Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity).[HAMAP-Rule:MF_01167]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/md/1mdx_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/md/1mdx_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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==See Also==
==See Also==
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*[[Aminotransferase|Aminotransferase]]
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*[[Aminotransferase 3D structures|Aminotransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus typhimurium loeffler 1892]]
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[[Category: Large Structures]]
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[[Category: Badger, J]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Buchanan, M D]]
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[[Category: Badger J]]
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[[Category: Buchanan, S G]]
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[[Category: Buchanan MD]]
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[[Category: Christopher, J A]]
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[[Category: Buchanan SG]]
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[[Category: Gajiwala, K S]]
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[[Category: Christopher JA]]
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[[Category: Hendle, J]]
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[[Category: Gajiwala KS]]
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[[Category: Muller-Dieckmann, H J]]
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[[Category: Hendle J]]
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[[Category: Newman, J M]]
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[[Category: Muller-Dieckmann H-J]]
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[[Category: Noland, B W]]
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[[Category: Newman JM]]
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[[Category: Rutter, M E]]
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[[Category: Noland BW]]
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[[Category: Sanderson, W E]]
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[[Category: Rutter ME]]
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[[Category: Sauder, J M]]
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[[Category: Sanderson WE]]
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[[Category: Tresser, J]]
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[[Category: Sauder JM]]
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[[Category: Wright, T A]]
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[[Category: Tresser J]]
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[[Category: Transferase]]
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[[Category: Wright TA]]
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[[Category: Type 1 aminotransferase fold]]
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Current revision

Crystal structure of ArnB transferase with pyridoxal 5' phosphate

PDB ID 1mdx

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