3cj8

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[[Image:3cj8.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase from Enterococcus faecalis V583==
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|PDB= 3cj8 |SIZE=350|CAPTION= <scene name='initialview01'>3cj8</scene>, resolution 1.95&Aring;
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<StructureSection load='3cj8' size='340' side='right'caption='[[3cj8]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:Mg+Binding+Site+For+Residue+A+301'>AC1</scene>, <scene name='pdbsite=AC2:Cl+Binding+Site+For+Residue+B+302'>AC2</scene>, <scene name='pdbsite=AC3:Cl+Binding+Site+For+Residue+C+303'>AC3</scene>, <scene name='pdbsite=AC4:Cl+Binding+Site+For+Residue+A+304'>AC4</scene>, <scene name='pdbsite=AC5:Cl+Binding+Site+For+Residue+B+305'>AC5</scene>, <scene name='pdbsite=AC6:Cl+Binding+Site+For+Residue+C+306'>AC6</scene>, <scene name='pdbsite=AC7:Cl+Binding+Site+For+Residue+A+307'>AC7</scene>, <scene name='pdbsite=AC8:Act+Binding+Site+For+Residue+A+316'>AC8</scene>, <scene name='pdbsite=AC9:Fmt+Binding+Site+For+Residue+A+308'>AC9</scene>, <scene name='pdbsite=BC1:Fmt+Binding+Site+For+Residue+B+309'>BC1</scene>, <scene name='pdbsite=BC2:Fmt+Binding+Site+For+Residue+C+310'>BC2</scene>, <scene name='pdbsite=BC3:Fmt+Binding+Site+For+Residue+A+311'>BC3</scene>, <scene name='pdbsite=BC4:Fmt+Binding+Site+For+Residue+B+312'>BC4</scene> and <scene name='pdbsite=BC5:Peg+Binding+Site+For+Residue+C+315'>BC5</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>
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<table><tr><td colspan='2'>[[3cj8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CJ8 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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|GENE= dapD, EF_1133 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=226185 Enterococcus faecalis V583])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00208 LbetaH], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam08503 DapD_N], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG2171 DapD]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cj8 OCA], [https://pdbe.org/3cj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cj8 RCSB], [https://www.ebi.ac.uk/pdbsum/3cj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cj8 ProSAT], [https://www.topsan.org/Proteins/MCSG/3cj8 TOPSAN]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cj8 OCA], [http://www.ebi.ac.uk/pdbsum/3cj8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3cj8 RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/DAPH_ENTFA DAPH_ENTFA] Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate (By similarity).
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== Evolutionary Conservation ==
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'''Crystal structure of 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase from Enterococcus faecalis V583'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cj/3cj8_consurf.spt"</scriptWhenChecked>
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3CJ8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Enterococcus_faecalis_v583 Enterococcus faecalis v583]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CJ8 OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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[[Category: Enterococcus faecalis v583]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Single protein]]
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</jmolCheckbox>
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[[Category: Bigelow, L.]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cj8 ConSurf].
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[[Category: Clancy, S.]]
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<div style="clear:both"></div>
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[[Category: Joachimiak, A.]]
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__TOC__
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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</StructureSection>
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[[Category: Tan, K.]]
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[[Category: Enterococcus faecalis]]
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[[Category: 2,3,4,5-tetrahydropyridine-2-carboxylate n-succinyltransferase]]
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[[Category: Large Structures]]
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[[Category: apc86892]]
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[[Category: Bigelow L]]
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[[Category: enterococcus faecalis v583]]
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[[Category: Clancy S]]
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[[Category: mcsg]]
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[[Category: Joachimiak A]]
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[[Category: midwest center for structural genomic]]
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[[Category: Tan K]]
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[[Category: protein structure initiative]]
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[[Category: psi-2]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:32:25 2008''
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Current revision

Crystal structure of 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase from Enterococcus faecalis V583

PDB ID 3cj8

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OCA

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