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6ire
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Complex structure of INAD PDZ45 and NORPA CC-PBM== | |
| - | + | <StructureSection load='6ire' size='340' side='right'caption='[[6ire]], [[Resolution|resolution]] 3.25Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ire]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IRE FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.25Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ire FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ire OCA], [https://pdbe.org/6ire PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ire RCSB], [https://www.ebi.ac.uk/pdbsum/6ire PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ire ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/PIPA_DROME PIPA_DROME] The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (By similarity). Essential component of the phototransduction pathway (PubMed:2457447). Essential downstream component of a hh-signaling pathway which regulates the Duox-dependent gut immune response to bacterial uracil; required for the activation of Cad99C and consequently Cad99C-dependent endosome formation, which is essential for the Duox-dependent production of reactive oxygen species (ROS) in response to intestinal bacterial infection (PubMed:25639794).[UniProtKB:Q9P212]<ref>PMID:2457447</ref> <ref>PMID:25639794</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Drosophila melanogaster]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Deng X]] | ||
| + | [[Category: Li J]] | ||
| + | [[Category: Liu W]] | ||
| + | [[Category: Ye F]] | ||
| + | [[Category: Zhang M]] | ||
Current revision
Complex structure of INAD PDZ45 and NORPA CC-PBM
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Categories: Drosophila melanogaster | Large Structures | Deng X | Li J | Liu W | Ye F | Zhang M
