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3la6

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Current revision (16:22, 1 November 2023) (edit) (undo)
 
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==Octameric kinase domain of the E. coli tyrosine kinase Wzc with bound ADP==
==Octameric kinase domain of the E. coli tyrosine kinase Wzc with bound ADP==
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<StructureSection load='3la6' size='340' side='right' caption='[[3la6]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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<StructureSection load='3la6' size='340' side='right'caption='[[3la6]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3la6]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LA6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LA6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3la6]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LA6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LA6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b2060, JW2045, wzc ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3la6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3la6 OCA], [http://pdbe.org/3la6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3la6 RCSB], [http://www.ebi.ac.uk/pdbsum/3la6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3la6 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3la6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3la6 OCA], [https://pdbe.org/3la6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3la6 RCSB], [https://www.ebi.ac.uk/pdbsum/3la6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3la6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/WZC_ECOLI WZC_ECOLI]] Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium. Phosphorylates udg.
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[https://www.uniprot.org/uniprot/WZC_ECOLI WZC_ECOLI] Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium. Phosphorylates udg.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Tyrosine kinase|Tyrosine kinase]]
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*[[Tyrosine kinase 3D structures|Tyrosine kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Bechet, E]]
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[[Category: Large Structures]]
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[[Category: Grangeasse, C]]
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[[Category: Bechet E]]
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[[Category: Gruszczyk, J]]
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[[Category: Grangeasse C]]
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[[Category: Gueguen-Chaignon, V]]
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[[Category: Gruszczyk J]]
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[[Category: Nessler, S]]
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[[Category: Gueguen-Chaignon V]]
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[[Category: Vigouroux, A]]
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[[Category: Nessler S]]
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[[Category: Bacterial protein kinase]]
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[[Category: Vigouroux A]]
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[[Category: Exopolysaccharide synthesis]]
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[[Category: Intermolecular phosphorylation]]
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[[Category: Nucleotide binding domain]]
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[[Category: Oligomerization]]
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[[Category: P-loop protein]]
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[[Category: Transferase]]
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[[Category: Walker a motif]]
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Current revision

Octameric kinase domain of the E. coli tyrosine kinase Wzc with bound ADP

PDB ID 3la6

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