Arginine repressor

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The structure of ArgR shows a DNA-binding domain at the acidic N-terminal and a basic C-terminal domain which contains the <scene name='55/554907/Cv/5'>intersubunit interaction sites</scene> and the <scene name='55/554907/Cv/10'>Arg binding site</scene>. Every Arg ligand interacts <scene name='55/554907/Cv/11'>with residues from 3 subunits</scene>.<ref>PMID:8594204</ref>
The structure of ArgR shows a DNA-binding domain at the acidic N-terminal and a basic C-terminal domain which contains the <scene name='55/554907/Cv/5'>intersubunit interaction sites</scene> and the <scene name='55/554907/Cv/10'>Arg binding site</scene>. Every Arg ligand interacts <scene name='55/554907/Cv/11'>with residues from 3 subunits</scene>.<ref>PMID:8594204</ref>
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</StructureSection>
 
==3D structures of arginine repressor==
==3D structures of arginine repressor==
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[[Arginine repressor 3D structures]]
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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</StructureSection>
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{{#tree:id=OrganizedByTopic|openlevels=0|
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*Arginine repressor
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**[[1b4a]] – GsArgR – ''Geobacillus stearothermophilus'' <br />
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**[[1f9n]] – BsArgR – ''Bacillus subtilis'' <br />
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**[[5cj9]] – ArgR – ''Bacillus halodurans'' <br />
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**[[5jvo]] – ArgR – ''Corynebacterium pseudotuberculosis'' <br />
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**[[3v4g]] – ArgR – ''Vibrio vulnificus'' <br />
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**[[3ere]] – MtArgR + DNA – ''Mycobacterium tuberculosis'' <br />
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**[[3fhz]], [[3laj]] – MtArgR + DNA + Arg <br />
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**[[3lap]] – MtArgR + DNA + canavanine <br />
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*Arginine repressor N terminal
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**[[1aoy]] – EcArgR N terminal - ''Escherichia coli'' - NMR<br />
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**[[1b4b]] – BsArgR N terminal <br />
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**[[2p5l]] – BsArgR N terminal + DNA <br />
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*Arginine repressor C terminal
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**[[1xxc]] – EcArgR C terminal <br />
 
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**[[2p5k]] – GsArgR C terminal <br />
 
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**[[3bue]] – MtArgR C terminal <br />
 
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**[[1xxa]], [[1xxb]] – EcArgR C terminal + Arg <br />
 
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**[[2p5m]] – BsArgR C terminal (mutant) + Arg <br />
 
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**[[2zfz]], [[3cag]] – MtArgR C terminal + Arg <br />
 
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}}
 
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

E. coli structure of arginine repressor C terminal hexamer complex with arginine (PDB entry 1xxb)

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References

  1. ↑ Ni J, Sakanyan V, Charlier D, Glansdorff N, Van Duyne GD. Structure of the arginine repressor from Bacillus stearothermophilus. Nat Struct Biol. 1999 May;6(5):427-32. PMID:10331868 doi:http://dx.doi.org/10.1038/8229
  2. ↑ Van Duyne GD, Ghosh G, Maas WK, Sigler PB. Structure of the oligomerization and L-arginine binding domain of the arginine repressor of Escherichia coli. J Mol Biol. 1996 Feb 23;256(2):377-91. PMID:8594204 doi:http://dx.doi.org/10.1006/jmbi.1996.0093

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Alexander Berchansky, Michal Harel

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