Arylamine N-acetyltransferase

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Human arylamine N-acetyltransferase 1 with active site Cys intermediate complex with Cl- (green) (PDB code 2pqt)

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↑ Wu H, Dombrovsky L, Tempel W, Martin F, Loppnau P, Goodfellow GH, Grant DM, Plotnikov AN. Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases. J Biol Chem. 2007 Oct 12;282(41):30189-97. Epub 2007 Jul 26. PMID:17656365 doi:10.1074/jbc.M704138200

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 NAT acetylates using a <scene name='48/486362/Cv/4'>catalytic Cys-His-Asp triad</scene> (magenta). <ref>PMID:17656365</ref> TYX is colored in salmon.
-</StructureSection>
 ==3D structures of arylamine N-acetyltransferase==
+[[Arylamine N-acetyltransferase 3D structures]]
-Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+</StructureSection>
-{{#tree:id=OrganizedByTopic|openlevels=0|
-*Arylamine N-acetyltransferase
-**[[1gx3]] – MsNAT – ''Mycobacterium smegmatis''<br />
-**[[1w5r]] – MsNAT (mutant)<br />
-**[[2bsz]] – RlNAT1 – ''Rhizobium loti''<br />
-**[[4nv8]] – RlNAT (mutant)<br />
-**[[2ija]] – hNAT1 (mutant) – human<br />
-**[[1w4t]] – NAT – ''Pseudomonas aeruginosa''<br />
-**[[3d9w]] – NAT – ''Nocardia farcinica''<br />
-**[[3lnb]] – NAT (mutant) – ''Bacillus anthracis''<br />
-**[[2vfb]], [[4c5p]] - MmNAT – ''Mycobacterium marinum''<br />
-**[[4bgf]] - NAT – ''Mycobacterium tuberculosis''<br />
-**[[1e2t]] - NAT – ''Salmonella typhimurium''<br />
-*Arylamine N-acetyltransferase binary complex
-**[[2pqt]] - hNAT1 + Cys intermediate<br />
-**[[2pfr]] – hNAT2 + CoA<br />
-**[[2vfc]] – MmNAT + CoA<br />
-**[[3ltw]] – MmNAT + hydralazine<br />
-**[[1w6f]] – MsNAT + anti-tubercular drug<br />
-**[[4b55]] – MmNAT + piperidinol derivative<br />
-**[[4nv7]] – RlNAT + CoA<br />
-}}
 == References ==
 <references/>
 [[Category:Topic Page]]