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1xqj
From Proteopedia
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==3.10 A Crystal structure of maspin, space group I 4 2 2== | ==3.10 A Crystal structure of maspin, space group I 4 2 2== | ||
| - | <StructureSection load='1xqj' size='340' side='right' caption='[[1xqj]], [[Resolution|resolution]] 3.10Å' scene=''> | + | <StructureSection load='1xqj' size='340' side='right'caption='[[1xqj]], [[Resolution|resolution]] 3.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1xqj]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1xqj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XQJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XQJ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1Å</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xqj OCA], [https://pdbe.org/1xqj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xqj RCSB], [https://www.ebi.ac.uk/pdbsum/1xqj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xqj ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/SPB5_HUMAN SPB5_HUMAN] Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[Serpin|Serpin]] | + | *[[Serpin 3D structures|Serpin 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Al-Ayyoubi | + | [[Category: Large Structures]] |
| - | [[Category: Gettins | + | [[Category: Al-Ayyoubi M]] |
| - | [[Category: Volz | + | [[Category: Gettins PG]] |
| - | + | [[Category: Volz K]] | |
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Current revision
3.10 A Crystal structure of maspin, space group I 4 2 2
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