3m2m

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Current revision (02:06, 21 November 2024) (edit) (undo)
 
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==Rat galectin-1 complex with lactose==
==Rat galectin-1 complex with lactose==
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<StructureSection load='3m2m' size='340' side='right' caption='[[3m2m]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
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<StructureSection load='3m2m' size='340' side='right'caption='[[3m2m]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3m2m]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M2M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3M2M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3m2m]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M2M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M2M FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LAT:BETA-LACTOSE'>LAT</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Lgals1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m2m OCA], [https://pdbe.org/3m2m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m2m RCSB], [https://www.ebi.ac.uk/pdbsum/3m2m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m2m ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3m2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m2m OCA], [http://pdbe.org/3m2m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3m2m RCSB], [http://www.ebi.ac.uk/pdbsum/3m2m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3m2m ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LEG1_RAT LEG1_RAT]] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates (By similarity).
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[https://www.uniprot.org/uniprot/LEG1_RAT LEG1_RAT] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m2/3m2m_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m2/3m2m_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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==See Also==
==See Also==
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*[[Galectin|Galectin]]
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*[[Galectin 3D structures|Galectin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Buffalo rat]]
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[[Category: Large Structures]]
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[[Category: Leffler, H]]
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[[Category: Rattus norvegicus]]
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[[Category: Lobsanov, Y D]]
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[[Category: Leffler H]]
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[[Category: Rini, J M]]
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[[Category: Lobsanov YD]]
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[[Category: Beta sandwich]]
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[[Category: Rini JM]]
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[[Category: Carbohydrate-binding protein]]
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[[Category: Extracellular matrix]]
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[[Category: Galectin-1]]
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[[Category: Lectin]]
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[[Category: Secreted]]
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Current revision

Rat galectin-1 complex with lactose

PDB ID 3m2m

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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