6j6v
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of heat shock factor 4-DBD== | |
+ | <StructureSection load='6j6v' size='340' side='right'caption='[[6j6v]], [[Resolution|resolution]] 1.20Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[6j6v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J6V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6J6V FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6j6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j6v OCA], [https://pdbe.org/6j6v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6j6v RCSB], [https://www.ebi.ac.uk/pdbsum/6j6v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6j6v ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Disease == | ||
+ | [https://www.uniprot.org/uniprot/HSF4_HUMAN HSF4_HUMAN] Early-onset lamellar cataract;Total early-onset cataract. The disease is caused by mutations affecting the gene represented in this entry. | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/HSF4_HUMAN HSF4_HUMAN] DNA-binding protein that specifically binds heat shock promoter elements (HSE). Isoform HSF4A represses transcription while the isoform HSF4B activates transcription.<ref>PMID:16371476</ref> | ||
- | + | ==See Also== | |
- | + | *[[Heat shock factor|Heat shock factor]] | |
- | + | == References == | |
- | [[Category: | + | <references/> |
- | [[Category: | + | __TOC__ |
- | [[Category: | + | </StructureSection> |
- | [[Category: Wang | + | [[Category: Homo sapiens]] |
- | [[Category: | + | [[Category: Large Structures]] |
+ | [[Category: Guo L]] | ||
+ | [[Category: Liu W]] | ||
+ | [[Category: Wang S]] | ||
+ | [[Category: Xiao ZY]] |
Current revision
Crystal structure of heat shock factor 4-DBD
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Categories: Homo sapiens | Large Structures | Guo L | Liu W | Wang S | Xiao ZY