6j90
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6j90 is ON HOLD Authors: Kaur, G., Sachdeva, E., Tiwari, P., Gupta, D., Ethayathulla, A.S., Kaur, P. Description: Crystal Structure of GyraseB N-Te...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of GyraseB N-Terminal Domain complex with ATP from Salmonella Typhi at 2.2A Resolution== | |
| + | <StructureSection load='6j90' size='340' side='right'caption='[[6j90]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6j90]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhi Salmonella enterica subsp. enterica serovar Typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6J90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6J90 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6j90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6j90 OCA], [https://pdbe.org/6j90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6j90 RCSB], [https://www.ebi.ac.uk/pdbsum/6j90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6j90 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GYRB_SALTI GYRB_SALTI] A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.[HAMAP-Rule:MF_01898] | ||
| - | + | ==See Also== | |
| - | + | *[[Gyrase 3D Structures|Gyrase 3D Structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Salmonella enterica subsp. enterica serovar Typhi]] |
| - | [[Category: | + | [[Category: Ethayathulla AS]] |
| - | [[Category: | + | [[Category: Gupta D]] |
| - | [[Category: Kaur | + | [[Category: Kaur G]] |
| - | [[Category: | + | [[Category: Kaur P]] |
| + | [[Category: Sachdeva E]] | ||
| + | [[Category: Tiwari P]] | ||
Current revision
Crystal Structure of GyraseB N-Terminal Domain complex with ATP from Salmonella Typhi at 2.2A Resolution
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