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6qh4
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6qh4 is ON HOLD Authors: Bailey, H.J., Chaikuid, A., Krysztofinska, E., Froese, D.S., Sorrell, F.J., Diaz-Saez, L., Kennedy, E., Edwards, A.M., Boun...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human Methylmalonyl-CoA epimerase (MCEE) p.Arg143Cys variant== | |
| - | + | <StructureSection load='6qh4' size='340' side='right'caption='[[6qh4]], [[Resolution|resolution]] 1.92Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6qh4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QH4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QH4 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.922Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr> |
| - | [[Category: Bailey | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qh4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qh4 OCA], [https://pdbe.org/6qh4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qh4 RCSB], [https://www.ebi.ac.uk/pdbsum/6qh4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qh4 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Disease == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/MCEE_HUMAN MCEE_HUMAN] Vitamin B12-unresponsive methylmalonic acidemia. Methylmalonyl-CoA epimerase deficiency (MCEED) [MIM:[https://omim.org/entry/251120 251120]: Autosomal recessive inborn error of amino acid metabolism, involving valine, threonine, isoleucine and methionine. This organic aciduria may present in the neonatal period with life-threatening metabolic acidosis, hyperammonemia, feeding difficulties, pancytopenia and coma. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:16752391</ref> |
| - | [[Category: Edwards | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/MCEE_HUMAN MCEE_HUMAN] |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bailey HJ]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Chaikuid A]] | ||
| + | [[Category: Diaz-Saez L]] | ||
| + | [[Category: Edwards AM]] | ||
| + | [[Category: Froese DS]] | ||
| + | [[Category: Kennedy E]] | ||
| + | [[Category: Krysztofinska E]] | ||
| + | [[Category: Sorrell FJ]] | ||
| + | [[Category: Yue WW]] | ||
Current revision
Crystal structure of human Methylmalonyl-CoA epimerase (MCEE) p.Arg143Cys variant
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Categories: Homo sapiens | Large Structures | Bailey HJ | Bountra C | Chaikuid A | Diaz-Saez L | Edwards AM | Froese DS | Kennedy E | Krysztofinska E | Sorrell FJ | Yue WW
