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6fhh

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==Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 22-mer modified Pol II CTD peptide with serine 5 thiophosphorylated.==
==Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 22-mer modified Pol II CTD peptide with serine 5 thiophosphorylated.==
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<StructureSection load='6fhh' size='340' side='right' caption='[[6fhh]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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<StructureSection load='6fhh' size='340' side='right'caption='[[6fhh]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6fhh]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FHH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FHH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6fhh]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Influenza_A_virus Influenza A virus] and [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/little_yellow-shouldered_bat/Guatemala/060/2010(H17N10)) Influenza A virus (A/little yellow-shouldered bat/Guatemala/060/2010(H17N10))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FHH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6FHH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=2RX:O-THIOPHOSPHONO-L-SERINE'>2RX</scene>, <scene name='pdbligand=TPS:THIAMIN+PHOSPHATE'>TPS</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2RX:O-THIOPHOSPHONO-L-SERINE'>2RX</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6fhh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fhh OCA], [https://pdbe.org/6fhh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6fhh RCSB], [https://www.ebi.ac.uk/pdbsum/6fhh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6fhh ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fhh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fhh OCA], [http://pdbe.org/6fhh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fhh RCSB], [http://www.ebi.ac.uk/pdbsum/6fhh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fhh ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/H6QM92_9INFA H6QM92_9INFA]
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==See Also==
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: RNA-directed RNA polymerase]]
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[[Category: Homo sapiens]]
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[[Category: Cusack, S]]
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[[Category: Influenza A virus]]
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[[Category: Lukarska, M]]
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[[Category: Large Structures]]
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[[Category: Influenza virus]]
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[[Category: Cusack S]]
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[[Category: Modified pol ii ctd peptide]]
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[[Category: Lukarska M]]
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[[Category: Rna-dependent rna polymerase]]
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[[Category: Viral protein]]
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Current revision

Crystal structure of bat influenza A/H17N10 polymerase with viral RNA promoter bound to a 22-mer modified Pol II CTD peptide with serine 5 thiophosphorylated.

PDB ID 6fhh

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