3nq7
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==Crystal structure of the mutant F71A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP== | ==Crystal structure of the mutant F71A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP== | ||
- | <StructureSection load='3nq7' size='340' side='right' caption='[[3nq7]], [[Resolution|resolution]] 1.44Å' scene=''> | + | <StructureSection load='3nq7' size='340' side='right'caption='[[3nq7]], [[Resolution|resolution]] 1.44Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3nq7]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3nq7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NQ7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NQ7 FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.443Å</td></tr> |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMP:6-HYDROXYURIDINE-5-PHOSPHATE'>BMP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
- | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nq7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nq7 OCA], [https://pdbe.org/3nq7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nq7 RCSB], [https://www.ebi.ac.uk/pdbsum/3nq7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nq7 ProSAT]</span></td></tr> |
- | + | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A] |
==See Also== | ==See Also== | ||
- | *[[Uridine 5'-monophosphate synthase|Uridine 5'-monophosphate synthase]] | + | *[[Uridine 5'-monophosphate synthase 3D structures|Uridine 5'-monophosphate synthase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Methanothermobacter thermautotrophicus]] |
- | [[Category: | + | [[Category: Almo SC]] |
- | [[Category: Fedorov | + | [[Category: Fedorov AA]] |
- | [[Category: | + | [[Category: Fedorov EV]] |
- | [[Category: | + | [[Category: Gerlt JA]] |
- | [[Category: | + | [[Category: Wood BM]] |
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Current revision
Crystal structure of the mutant F71A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP
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