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5qn0

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'''Unreleased structure'''
 
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The entry 5qn0 is ON HOLD
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==Group deposition of library data - Crystal Structure of EcDsbA after initial refinement with no ligand modelled (structure G6_2)==
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<StructureSection load='5qn0' size='340' side='right'caption='[[5qn0]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
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Authors: Ilyichova, O.V., Bentley, M.R., Doak, B.C., Scanlon, M.J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5qn0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QN0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QN0 FirstGlance]. <br>
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Description: Group deposition of library data -Crystal Structure of EcDsbA after initial refinement with no ligand modelled (structure G6_2)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.007&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qn0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qn0 OCA], [https://pdbe.org/5qn0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qn0 RCSB], [https://www.ebi.ac.uk/pdbsum/5qn0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qn0 ProSAT]</span></td></tr>
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[[Category: Doak, B.C]]
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</table>
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[[Category: Ilyichova, O.V]]
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== Function ==
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[[Category: Scanlon, M.J]]
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[https://www.uniprot.org/uniprot/DSBA_ECOLI DSBA_ECOLI] Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. Required for pilus biogenesis. PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.<ref>PMID:1429594</ref> <ref>PMID:22267510</ref>
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[[Category: Bentley, M.R]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Bentley MR]]
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[[Category: Doak BC]]
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[[Category: Ilyichova OV]]
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[[Category: Scanlon MJ]]

Current revision

Group deposition of library data - Crystal Structure of EcDsbA after initial refinement with no ligand modelled (structure G6_2)

PDB ID 5qn0

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