3ckk

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(New page: 200px {{Structure |PDB= 3ckk |SIZE=350|CAPTION= <scene name='initialview01'>3ckk</scene>, resolution 1.55&Aring; |SITE= <scene name='pdbsite=AC1:Sam+Binding+Site+...)
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[[Image:3ckk.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of human methyltransferase-like protein 1==
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|PDB= 3ckk |SIZE=350|CAPTION= <scene name='initialview01'>3ckk</scene>, resolution 1.55&Aring;
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<StructureSection load='3ckk' size='340' side='right'caption='[[3ckk]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
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|SITE= <scene name='pdbsite=AC1:Sam+Binding+Site+For+Residue+A+301'>AC1</scene> and <scene name='pdbsite=AC2:Gol+Binding+Site+For+Residue+A+302'>AC2</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>
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<table><tr><td colspan='2'>[[3ckk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CKK FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine-N(7)-)-methyltransferase tRNA (guanine-N(7)-)-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.33 2.1.1.33] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
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|GENE= METTL1, C12orf1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam02390 Methyltransf_4]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ckk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ckk OCA], [https://pdbe.org/3ckk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ckk RCSB], [https://www.ebi.ac.uk/pdbsum/3ckk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ckk ProSAT]</span></td></tr>
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|RELATEDENTRY=
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ckk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ckk OCA], [http://www.ebi.ac.uk/pdbsum/3ckk PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3ckk RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/TRMB_HUMAN TRMB_HUMAN] Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.<ref>PMID:12403464</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ck/3ckk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ckk ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of human methyltransferase-like protein 1'''
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==See Also==
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*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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3CKK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CKK OCA].
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: tRNA (guanine-N(7)-)-methyltransferase]]
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[[Category: Arrowsmith CH]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Bochkarev A]]
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[[Category: Bochkarev, A.]]
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[[Category: Bountra C]]
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[[Category: Bountra, C.]]
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[[Category: Dobrovetsky E]]
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[[Category: Dobrovetsky, E.]]
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[[Category: Dong A]]
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[[Category: Dong, A.]]
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[[Category: Edwards AM]]
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[[Category: Edwards, A M.]]
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[[Category: Min J]]
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[[Category: Min, J.]]
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[[Category: Plotnikov AN]]
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[[Category: Plotnikov, A N.]]
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[[Category: Weigelt J]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Wu H]]
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[[Category: Weigelt, J.]]
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[[Category: Zeng H]]
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[[Category: Wu, H.]]
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[[Category: Zeng, H.]]
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[[Category: methyltransferase]]
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[[Category: mettl1]]
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[[Category: s-adenosyl-l-methionine]]
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[[Category: sgc]]
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[[Category: structural genomic]]
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[[Category: structural genomics consortium]]
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[[Category: trna processing]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 2 12:00:23 2008''
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Current revision

Crystal structure of human methyltransferase-like protein 1

PDB ID 3ckk

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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