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6qs0
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==NMR structure of BB_A03, Borrelia burgdorferi outer surface lipoprotein== | |
| + | <StructureSection load='6qs0' size='340' side='right'caption='[[6qs0]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6qs0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Borreliella_burgdorferi_B31 Borreliella burgdorferi B31]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QS0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QS0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qs0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qs0 OCA], [https://pdbe.org/6qs0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qs0 RCSB], [https://www.ebi.ac.uk/pdbsum/6qs0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qs0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Y2503_BORBU Y2503_BORBU] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | BBA03 is a Borrelia burgdorferi outer surface lipoprotein encoded on one of the most conserved plasmids in Borrelia genome, linear plasmid 54 (lp54). Although many of its genes have been identified as contributing or essential for spirochete fitness in vivo, the majority of the proteins encoded on this plasmid have no known function and lack homologs in other organisms. In this paper, we report the solution NMR structure of the B. burgdorferi outer surface lipoprotein BBA03, which is known to provide a competitive advantage to the bacteria during the transmission from tick vector to mammalian host. BBA03 shows structural homology to other outer surface lipoproteins reflecting their genetic and evolutionary relatedness. Analysis of the structure reveals a pore in BBA03, which could potentially bind lipids. | ||
| - | + | Structural and Functional Analysis of BBA03, Borrelia burgdorferi Competitive Advantage Promoting Outer Surface Lipoprotein.,Fridmanis J, Bobrovs R, Brangulis K, Tars K, Jaudzems K Pathogens. 2020 Oct 9;9(10):826. doi: 10.3390/pathogens9100826. PMID:33050189<ref>PMID:33050189</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| - | [[Category: Brangulis | + | <div class="pdbe-citations 6qs0" style="background-color:#fffaf0;"></div> |
| - | [[Category: Fridmanis | + | == References == |
| - | [[Category: Jaudzems | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Borreliella burgdorferi B31]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Brangulis K]] | ||
| + | [[Category: Fridmanis J]] | ||
| + | [[Category: Jaudzems K]] | ||
Current revision
NMR structure of BB_A03, Borrelia burgdorferi outer surface lipoprotein
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