5zb2

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==Crystal structure of Rad7 and Elc1 complex in yeast==
==Crystal structure of Rad7 and Elc1 complex in yeast==
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<StructureSection load='5zb2' size='340' side='right' caption='[[5zb2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='5zb2' size='340' side='right'caption='[[5zb2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5zb2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZB2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZB2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5zb2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZB2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZB2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9FO:3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57-nonadecaoxanonapentacontane-1,59-diol'>9FO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=P33:3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL'>P33</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3000054&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zb2 OCA], [http://pdbe.org/5zb2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zb2 RCSB], [http://www.ebi.ac.uk/pdbsum/5zb2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zb2 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9FO:3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57-nonadecaoxanonapentacontane-1,59-diol'>9FO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=P33:3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL'>P33</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zb2 OCA], [https://pdbe.org/5zb2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zb2 RCSB], [https://www.ebi.ac.uk/pdbsum/5zb2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zb2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RAD7_YEAST RAD7_YEAST]] Component of the global genome repair (GGR) complex which promotes global genome nucleotide excision repair (GG-NER) which removes DNA damage from nontranscribing DNA. This protein is one of 10 proteins (RAD1, 2,3,4,7,10,14, 16,23 and MMS19) involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents.<ref>PMID:10601031</ref> <ref>PMID:15177043</ref> [[http://www.uniprot.org/uniprot/ELOC_YEAST ELOC_YEAST]] Prevents degradation of interacting proteins like PCL6 by the proteasome.<ref>PMID:11864988</ref>
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[https://www.uniprot.org/uniprot/RAD7_YEAST RAD7_YEAST] Component of the global genome repair (GGR) complex which promotes global genome nucleotide excision repair (GG-NER) which removes DNA damage from nontranscribing DNA. This protein is one of 10 proteins (RAD1, 2,3,4,7,10,14, 16,23 and MMS19) involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents.<ref>PMID:10601031</ref> <ref>PMID:15177043</ref>
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==See Also==
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*[[Elongation factor 3D structures|Elongation factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Huo, Y]]
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[[Category: Large Structures]]
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[[Category: Jiang, T]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Liu, L]]
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[[Category: Huo Y]]
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[[Category: Complex]]
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[[Category: Jiang T]]
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[[Category: Dna binding protein-ligase complex]]
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[[Category: Liu L]]
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[[Category: Ligase]]
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[[Category: Lrr]]
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[[Category: Ubiquitin ligase]]
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Current revision

Crystal structure of Rad7 and Elc1 complex in yeast

PDB ID 5zb2

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