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3x03

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==Crystal structure of PIP4KIIBETA complex with AMPPNP==
==Crystal structure of PIP4KIIBETA complex with AMPPNP==
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<StructureSection load='3x03' size='340' side='right' caption='[[3x03]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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<StructureSection load='3x03' size='340' side='right'caption='[[3x03]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3x03]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3X03 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3X03 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3x03]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3X03 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3X03 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wzz|3wzz]], [[3x01|3x01]], [[3x02|3x02]], [[3x04|3x04]], [[3x05|3x05]], [[3x06|3x06]], [[3x07|3x07]], [[3x08|3x08]], [[3x09|3x09]], [[3x0a|3x0a]], [[3x0b|3x0b]], [[3x0c|3x0c]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PIP4K2B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3x03 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3x03 OCA], [https://pdbe.org/3x03 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3x03 RCSB], [https://www.ebi.ac.uk/pdbsum/3x03 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3x03 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/1-phosphatidylinositol-5-phosphate_4-kinase 1-phosphatidylinositol-5-phosphate 4-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.149 2.7.1.149] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3x03 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3x03 OCA], [http://pdbe.org/3x03 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3x03 RCSB], [http://www.ebi.ac.uk/pdbsum/3x03 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3x03 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PI42B_HUMAN PI42B_HUMAN]] Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.<ref>PMID:9038203</ref>
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[https://www.uniprot.org/uniprot/PI42B_HUMAN PI42B_HUMAN] Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate.<ref>PMID:9038203</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 1-phosphatidylinositol-5-phosphate 4-kinase]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Large Structures]]
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[[Category: Asara, J A]]
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[[Category: Asara JA]]
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[[Category: Cantley, L C]]
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[[Category: Cantley LC]]
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[[Category: Daikoku, T]]
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[[Category: Daikoku T]]
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[[Category: Dimitoris, A]]
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[[Category: Dimitoris A]]
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[[Category: Emerling, B]]
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[[Category: Emerling B]]
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[[Category: Ishida, T]]
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[[Category: Ishida T]]
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[[Category: Kahoud, E R]]
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[[Category: Kahoud ER]]
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[[Category: Lo, Y H]]
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[[Category: Lo YH]]
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[[Category: Locasale, J W]]
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[[Category: Locasale JW]]
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[[Category: Sasaki, A T]]
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[[Category: Sasaki AT]]
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[[Category: Sasaki, M]]
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[[Category: Sasaki M]]
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[[Category: Senda, M]]
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[[Category: Senda M]]
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[[Category: Senda, T]]
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[[Category: Senda T]]
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[[Category: Shimada, I]]
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[[Category: Shimada I]]
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[[Category: Sumita, K]]
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[[Category: Sumita K]]
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[[Category: Takano, T]]
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[[Category: Takano T]]
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[[Category: Takeuchi, K]]
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[[Category: Takeuchi K]]
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[[Category: Terakawa, J]]
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[[Category: Terakawa J]]
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[[Category: Yokota, T]]
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[[Category: Yokota T]]
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[[Category: Yoshino, H]]
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[[Category: Yoshino H]]
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[[Category: Zhang, Y]]
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[[Category: Zhang Y]]
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[[Category: Lipid kinase]]
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[[Category: Phosphoinositide signaling]]
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[[Category: Transferase]]
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Current revision

Crystal structure of PIP4KIIBETA complex with AMPPNP

PDB ID 3x03

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