Alpha-lactalbumin
From Proteopedia
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<StructureSection load='1hml' size='350' side='right' caption='Human α-lactalbumin complex with sulfate, Zn+2 (grey) and Ca+2 (green) ions (PDB code [[1hml]]).' scene='46/468232/Cv/1' pspeed='8'> | <StructureSection load='1hml' size='350' side='right' caption='Human α-lactalbumin complex with sulfate, Zn+2 (grey) and Ca+2 (green) ions (PDB code [[1hml]]).' scene='46/468232/Cv/1' pspeed='8'> | ||
== Function == | == Function == | ||
| - | '''Alpha-lactalbumin''' (LCA) is the albumin contained in milk and obtained from whey<ref>PMID:10818224</ref>. LCA is the regulatory subunit of the lactose synthase heterodimer which produces lactose by transferring galactose moieties to glucose. | + | '''Alpha-lactalbumin''' (LCA) is the albumin contained in milk and obtained from whey<ref>PMID:10818224</ref>. LCA is the regulatory subunit of the '''lactose synthase''' heterodimer which produces lactose by transferring galactose moieties to glucose. |
== Relevance == | == Relevance == | ||
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</StructureSection> | </StructureSection> | ||
| - | == 3D Structures of α-lactalbumin == | ||
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| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *α-lactalbumin | ||
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| - | **[[1alc]] – LCA – baboon | ||
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| - | **[[1hml]], [[1b9o]], [[3b0i]], [[3b0o]] – hLCA –human | ||
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| - | **[[1a4v]] – hLCA Ca-binding domain<br /> | ||
| - | **[[1cb3]] – hLCA residues 1-13 - NMR<br /> | ||
| - | **[[1hfx]] – LCA – guinea pig | ||
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| - | **[[1hfy]], [[3b0k]] – gLCA – goat | ||
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| - | **[[1hmk]], [[1fkq]], [[1fkv]] – gLCA (mutant) | ||
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| - | **[[1f6r]], [[1f6s]], [[2g4n]], [[6ip9]] – bLCA - bovine | ||
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| - | **[[1hfz]] – bLCA (mutant) | ||
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| - | *α-LCA complexes | ||
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| - | **[[1nf5]] – mLCA + β-1,4-galactosyl transferase + glucose – mouse | ||
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| - | **[[1nhe]] – mLCA + β-1,4-galactosyl transferase + UDP | ||
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| - | **[[1nkh]] – mLCA + β-1,4-galactosyl transferase + UDP + Mn | ||
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| - | **[[1nmm]] – mLCA + β-1,4-galactosyl transferase (mutant) | ||
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| - | **[[1nqi]] - mLCA + β-1,4-galactosyl transferase | ||
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| - | **[[1nwg]] - mLCA + β-1,4-galactosyl transferase + butanoyl-glucosamine | ||
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| - | **[[1o23]] - mLCA + β-1,4-galactosyl transferase + UDP-glucose | ||
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| - | **[[1oqm]] - mLCA + β-1,4-galactosyl transferase + UDP-acetyl-galactosamine | ||
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| - | **[[1pzy]] - mLCA (mutant) + β-1,4-galactosyl transferase + acetyl-glucosamine + UDP + Mn | ||
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| - | **[[1yro]] - mLCA + β-1,4-galactosyl transferase + UDP-galactose + Mn | ||
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| - | **[[1fyc]] - mLCA (mutant) + β-1,4-galactosyl transferase + UDP-galactose + Ca | ||
| - | **[[2fyd]], [[2fyc]] - mLCA (mutant) + β-1,4-galactosyl transferase + glucose + UDP-acetylgalactosamine + Mn<br /> | ||
| - | **[[4l41]] - hLCA + β-1,4-galactosyl transferase (mutant)<br /> | ||
| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
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References
- ↑ Permyakov EA, Berliner LJ. alpha-Lactalbumin: structure and function. FEBS Lett. 2000 May 19;473(3):269-74. PMID:10818224
