This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


6jj3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "6jj3" [edit=sysop:move=sysop])
Current revision (10:38, 27 March 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 6jj3 is ON HOLD
+
==BRD4 in complex with 138A==
 +
<StructureSection load='6jj3' size='340' side='right'caption='[[6jj3]], [[Resolution|resolution]] 1.72&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[6jj3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JJ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JJ3 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.718&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BS6:2-methoxy-N-[2-methyl-6-(4-methylpiperazin-1-yl)-3-oxidanylidene-2,7-diazatricyclo[6.3.1.0^{4,12}]dodeca-1(12),4,6,8,10-pentaen-9-yl]benzenesulfonamide'>BS6</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jj3 OCA], [https://pdbe.org/6jj3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jj3 RCSB], [https://www.ebi.ac.uk/pdbsum/6jj3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jj3 ProSAT]</span></td></tr>
 +
</table>
 +
== Disease ==
 +
[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
-
Authors: Xu, J., Chen, Y., Jiang, F., Zhu, J.
+
==See Also==
-
 
+
*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
-
Description: BRD4 in complex with 138A
+
== References ==
-
[[Category: Unreleased Structures]]
+
<references/>
-
[[Category: Xu, J]]
+
__TOC__
-
[[Category: Zhu, J]]
+
</StructureSection>
-
[[Category: Jiang, F]]
+
[[Category: Homo sapiens]]
-
[[Category: Chen, Y]]
+
[[Category: Large Structures]]
 +
[[Category: Chen Y]]
 +
[[Category: Jiang F]]
 +
[[Category: Xu J]]
 +
[[Category: Zhu J]]

Current revision

BRD4 in complex with 138A

PDB ID 6jj3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6jj3"
Personal tools