5zch

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==Crystal structure of OsPP2C50 I267W:OsPYL/RCAR3 with (+)-ABA==
==Crystal structure of OsPP2C50 I267W:OsPYL/RCAR3 with (+)-ABA==
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<StructureSection load='5zch' size='340' side='right' caption='[[5zch]], [[Resolution|resolution]] 2.47&Aring;' scene=''>
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<StructureSection load='5zch' size='340' side='right'caption='[[5zch]], [[Resolution|resolution]] 2.47&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5zch]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZCH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZCH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5zch]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa_Japonica_Group Oryza sativa Japonica Group]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZCH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZCH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A8S:(2Z,4E)-5-[(1S)-1-HYDROXY-2,6,6-TRIMETHYL-4-OXOCYCLOHEX-2-EN-1-YL]-3-METHYLPENTA-2,4-DIENOIC+ACID'>A8S</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.474&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoprotein_phosphatase Phosphoprotein phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.16 3.1.3.16] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A8S:(2Z,4E)-5-[(1S)-1-HYDROXY-2,6,6-TRIMETHYL-4-OXOCYCLOHEX-2-EN-1-YL]-3-METHYLPENTA-2,4-DIENOIC+ACID'>A8S</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zch FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zch OCA], [http://pdbe.org/5zch PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zch RCSB], [http://www.ebi.ac.uk/pdbsum/5zch PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zch ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zch FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zch OCA], [https://pdbe.org/5zch PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zch RCSB], [https://www.ebi.ac.uk/pdbsum/5zch PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zch ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PYL3_ORYSJ PYL3_ORYSJ]] Involved in abscisic acid (ABA) signaling during seed germination and abiotic stress response. Acts as positive regulator of ABA-mediated inhibition of seed germination, and tolerance to drought and cold stresses (PubMed:26362328). Together with PP2C50 and SAPK10, may form an ABA signaling module involved in stress response (PubMed:28827170). Inhibits the protein phosphatases PP2C06 and PP2C09 when activated by abscisic acid (ABA) (PubMed:24743650).<ref>PMID:24743650</ref> <ref>PMID:26362328</ref> <ref>PMID:28827170</ref>
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[https://www.uniprot.org/uniprot/P2C50_ORYSJ P2C50_ORYSJ]
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== References ==
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<references/>
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==See Also==
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*[[Protein phosphatase 3D structures|Protein phosphatase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Phosphoprotein phosphatase]]
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[[Category: Large Structures]]
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[[Category: Han, S]]
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[[Category: Oryza sativa Japonica Group]]
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[[Category: Lee, S]]
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[[Category: Han S]]
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[[Category: Aba]]
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[[Category: Lee S]]
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[[Category: Abscisic acid]]
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[[Category: Complex]]
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[[Category: Phosphatase]]
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[[Category: Plant protein]]
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[[Category: Receptor]]
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[[Category: Stress]]
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Current revision

Crystal structure of OsPP2C50 I267W:OsPYL/RCAR3 with (+)-ABA

PDB ID 5zch

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