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6o62
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Sec4p, a Rab family GTPase from Candida albicans== | |
| + | <StructureSection load='6o62' size='340' side='right'caption='[[6o62]], [[Resolution|resolution]] 1.88Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6o62]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans_SC5314 Candida albicans SC5314]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6O62 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6O62 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.88Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6o62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6o62 OCA], [https://pdbe.org/6o62 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6o62 RCSB], [https://www.ebi.ac.uk/pdbsum/6o62 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6o62 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SEC4_CANAL SEC4_CANAL] Involved in exocytosis. Maybe by regulating the binding and fusion of secretory vesicles with the cell surface. The GTP-bound form of SEC4 may interact with an effector, thereby stimulating its activity and leading to exocytotic fusion. SEC4 may be an upstream activator of the 19.5S SEC8/SEC15 particle. SEC4 probably interacts directly with SEC8; it could serve as the attachment site for the SEC8/SEC15 particle (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Candida albicans SC5314]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Di Leo R]] |
| - | [[Category: | + | [[Category: Savchenko A]] |
| - | [[Category: | + | [[Category: Skarina T]] |
| + | [[Category: Stogios PJ]] | ||
Current revision
Crystal structure of Sec4p, a Rab family GTPase from Candida albicans
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