6qtc
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==tSH2 domain of transcription elongation factor Spt6 complexed with tyrosine phosphorylated CTD== | |
| + | <StructureSection load='6qtc' size='340' side='right'caption='[[6qtc]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6qtc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_glabrata Candida glabrata]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QTC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6QTC FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6qtc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qtc OCA], [https://pdbe.org/6qtc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6qtc RCSB], [https://www.ebi.ac.uk/pdbsum/6qtc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6qtc ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SPT6_CANGA SPT6_CANGA] Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[Elongation factor 3D structures|Elongation factor 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Brazda P]] | ||
| + | [[Category: Krejcikova M]] | ||
| + | [[Category: Kubicek K]] | ||
| + | [[Category: Smirakova E]] | ||
| + | [[Category: Stefl R]] | ||
Current revision
tSH2 domain of transcription elongation factor Spt6 complexed with tyrosine phosphorylated CTD
| |||||||||||
