4b2m

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<StructureSection load='4b2m' size='340' side='right'caption='[[4b2m]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='4b2m' size='340' side='right'caption='[[4b2m]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4b2m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hals3 Hals3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B2M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B2M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4b2m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Halobacterium_salinarum_R1 Halobacterium salinarum R1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B2M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B2M FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RBF:RIBOFLAVIN'>RBF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=4AW:4-AZATRYPTOPHAN'>4AW</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4AW:4-AZATRYPTOPHAN'>4AW</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=RBF:RIBOFLAVIN'>RBF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cc8|2cc8]], [[2ccb|2ccb]], [[2vx9|2vx9]], [[4b2h|4b2h]], [[4b2j|4b2j]], [[4b2k|4b2k]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b2m OCA], [https://pdbe.org/4b2m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b2m RCSB], [https://www.ebi.ac.uk/pdbsum/4b2m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b2m ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b2m OCA], [http://pdbe.org/4b2m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4b2m RCSB], [http://www.ebi.ac.uk/pdbsum/4b2m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4b2m ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DODEC_HALS3 DODEC_HALS3]] May function as storage protein that sequesters riboflavin and related compounds, thereby protecting the cell against undesirable reactions mediated by the free flavins. Binds and sequesters riboflavin, lumiflavin and lumichrome. Can also bind FAD and FMN (in vitro), but has low affinity for FAD and even lower affinity for FMN. Protects bound flavins against light damage; Trp-36 rapidly quenches the flavin excited state. Promotes the conversion of bound riboflavin to lumichrome.<ref>PMID:12679016</ref> <ref>PMID:16460756</ref> <ref>PMID:17027852</ref> <ref>PMID:19224924</ref> <ref>PMID:20408700</ref>
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[https://www.uniprot.org/uniprot/DODEC_HALS3 DODEC_HALS3] May function as storage protein that sequesters riboflavin and related compounds, thereby protecting the cell against undesirable reactions mediated by the free flavins. Binds and sequesters riboflavin, lumiflavin and lumichrome. Can also bind FAD and FMN (in vitro), but has low affinity for FAD and even lower affinity for FMN. Protects bound flavins against light damage; Trp-36 rapidly quenches the flavin excited state. Promotes the conversion of bound riboflavin to lumichrome.<ref>PMID:12679016</ref> <ref>PMID:16460756</ref> <ref>PMID:17027852</ref> <ref>PMID:19224924</ref> <ref>PMID:20408700</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Hals3]]
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[[Category: Halobacterium salinarum R1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Budisa, N]]
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[[Category: Budisa N]]
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[[Category: Dreuw, A]]
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[[Category: Dreuw A]]
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[[Category: Grininger, M]]
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[[Category: Grininger M]]
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[[Category: Hoesl, M]]
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[[Category: Hoesl M]]
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[[Category: Oesterhelt, D]]
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[[Category: Oesterhelt D]]
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[[Category: Serdjukow, S]]
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[[Category: Serdjukow S]]
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[[Category: Staudt, H]]
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[[Category: Staudt H]]
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[[Category: Wachtveitl, J]]
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[[Category: Wachtveitl J]]
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[[Category: Flavoprotein]]
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[[Category: Protein reaction control]]
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Current revision

COMPLEXES OF DODECIN WITH FLAVIN AND FLAVIN-LIKE LIGANDS

PDB ID 4b2m

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