This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5zx9

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:29, 27 March 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 5zx9 is ON HOLD until May 18 2020
+
==Crystal structure of apo form fibronectin-binding protein Apa from Mycobacterium tuberculosis==
-
 
+
<StructureSection load='5zx9' size='340' side='right'caption='[[5zx9]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
-
Authors: Gao, J., Liu, W.D., Chen, C.C., Guo, R.T.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[5zx9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZX9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZX9 FirstGlance]. <br>
-
Description: Crystal structure of a protein from Mycobacterium
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-
[[Category: Liu, W.D]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zx9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zx9 OCA], [https://pdbe.org/5zx9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zx9 RCSB], [https://www.ebi.ac.uk/pdbsum/5zx9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zx9 ProSAT]</span></td></tr>
-
[[Category: Chen, C.C]]
+
</table>
-
[[Category: Guo, R.T]]
+
== Function ==
-
[[Category: Gao, J]]
+
[https://www.uniprot.org/uniprot/APA_MYCTU APA_MYCTU] A potent antigen in animals immunized with live bacteria, it induces a strong delayed-type hypersensitivity (DTH) in immunized animals (PubMed:10531201). Elicits a mostly Th1 type of T-cell response in healthy humans; induces IFN-gamma production from CD4(+) and CD8(+) cells (PubMed:12654810). Functions as an adhesin, binds to mouse macrophages via mannose residues (PubMed:10531201, PubMed:25359607). Might interact via host CD209 (PubMed:16092920).<ref>PMID:10531201</ref> <ref>PMID:12654810</ref> <ref>PMID:16092920</ref> <ref>PMID:25359607</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Mycobacterium tuberculosis H37Rv]]
 +
[[Category: Chen CC]]
 +
[[Category: Gao J]]
 +
[[Category: Guo RT]]
 +
[[Category: Liu WD]]

Current revision

Crystal structure of apo form fibronectin-binding protein Apa from Mycobacterium tuberculosis

PDB ID 5zx9

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/5zx9"
Personal tools