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6i0r

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<StructureSection load='6i0r' size='340' side='right'caption='[[6i0r]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='6i0r' size='340' side='right'caption='[[6i0r]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6i0r]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I0R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6I0R FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6i0r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6I0R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6I0R FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=H2S:HYDROSULFURIC+ACID'>H2S</scene>, <scene name='pdbligand=QAT:5-mercaptopyridine-2,3-dicarboxylic+acid'>QAT</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6i0k|6i0k]], [[6i0p|6i0p]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=H2S:HYDROSULFURIC+ACID'>H2S</scene>, <scene name='pdbligand=QAT:5-mercaptopyridine-2,3-dicarboxylic+acid'>QAT</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Quinolinate_synthase Quinolinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.72 2.5.1.72] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6i0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i0r OCA], [https://pdbe.org/6i0r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6i0r RCSB], [https://www.ebi.ac.uk/pdbsum/6i0r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6i0r ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6i0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6i0r OCA], [http://pdbe.org/6i0r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6i0r RCSB], [http://www.ebi.ac.uk/pdbsum/6i0r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6i0r ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/NADA_THEMA NADA_THEMA]] Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity).
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[https://www.uniprot.org/uniprot/NADA_THEMA NADA_THEMA] Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Quinolinate synthase]]
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[[Category: Thermotoga maritima MSB8]]
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[[Category: Fontecilla-Camps, J C]]
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[[Category: Fontecilla-Camps JC]]
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[[Category: Volbeda, A]]
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[[Category: Volbeda A]]
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[[Category: Iron sulfur cluster]]
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[[Category: Nad biosynthesis]]
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[[Category: Transferase]]
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Current revision

Structure of quinolinate synthase in complex with 5-mercaptopyridine-2,3-dicarboxylic acid

PDB ID 6i0r

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