4d4k

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<StructureSection load='4d4k' size='340' side='right'caption='[[4d4k]], [[Resolution|resolution]] 3.24&Aring;' scene=''>
<StructureSection load='4d4k' size='340' side='right'caption='[[4d4k]], [[Resolution|resolution]] 3.24&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4d4k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D4K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D4K FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4d4k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D4K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D4K FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BKE:7-(4-METHOXYPHENYL)-5-PHENYL-3,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-ONE'>BKE</scene>, <scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.24&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4d4j|4d4j]], [[4d4l|4d4l]], [[4d4m|4d4m]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BKE:7-(4-METHOXYPHENYL)-5-PHENYL-3,7-DIHYDRO-4H-PYRROLO[2,3-D]PYRIMIDIN-4-ONE'>BKE</scene>, <scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d4k OCA], [http://pdbe.org/4d4k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4d4k RCSB], [http://www.ebi.ac.uk/pdbsum/4d4k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4d4k ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d4k OCA], [https://pdbe.org/4d4k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d4k RCSB], [https://www.ebi.ac.uk/pdbsum/4d4k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d4k ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/F263_HUMAN F263_HUMAN]] Synthesis and degradation of fructose 2,6-bisphosphate.
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[https://www.uniprot.org/uniprot/F263_HUMAN F263_HUMAN] Synthesis and degradation of fructose 2,6-bisphosphate.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bennett, N]]
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[[Category: Bennett N]]
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[[Category: Critchlow, S]]
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[[Category: Critchlow S]]
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[[Category: Davies, G]]
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[[Category: Davies G]]
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[[Category: Debreczeni, J E]]
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[[Category: Debreczeni JE]]
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[[Category: Evans, N]]
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[[Category: Evans N]]
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[[Category: Holdgate, G]]
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[[Category: Holdgate G]]
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[[Category: Jones, N P]]
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[[Category: Jones NP]]
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[[Category: Leach, L]]
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[[Category: Leach L]]
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[[Category: Maman, S]]
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[[Category: Maman S]]
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[[Category: McLoughlin, S]]
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[[Category: McLoughlin S]]
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[[Category: Preston, M]]
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[[Category: Preston M]]
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[[Category: Rigoreau, L]]
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[[Category: Rigoreau L]]
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[[Category: Stgallay, S A]]
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[[Category: Stgallay SA]]
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[[Category: Thomas, A]]
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[[Category: Thomas A]]
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[[Category: Walker, G]]
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[[Category: Walker G]]
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[[Category: Walsch, J]]
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[[Category: Walsch J]]
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[[Category: Ward, R A]]
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[[Category: Ward RA]]
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[[Category: Wheatley, E]]
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[[Category: Wheatley E]]
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[[Category: Winter, J]]
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[[Category: Winter J]]
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[[Category: Oncology]]
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[[Category: Sugar kinase]]
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[[Category: Transferase]]
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[[Category: Warburg effect]]
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Current revision

human PFKFB3 in complex with a pyrrolopyrimidone compound

PDB ID 4d4k

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