Acetyl-CoA carboxylase 3D structures
From Proteopedia
(Difference between revisions)
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**[[6g2d]] – hACC1 – human – Cryo EM<br /> | **[[6g2d]] – hACC1 – human – Cryo EM<br /> | ||
**[[5csk]], [[5csl]] – yACC - yeast <br /> | **[[5csk]], [[5csl]] – yACC - yeast <br /> | ||
| + | **[[7w5u]] – ACC β chain – ''Streptomyces antibioticus''<br /> | ||
*Biotin carboxyl carrier protein (BCCP) domain | *Biotin carboxyl carrier protein (BCCP) domain | ||
| - | **[[1bnc]], [[1dv1]] - EcBCCP – ''Escherichia coli''<br /> | ||
| - | **[[2gps]], [[2gpw]], [[3g8d]] - EcBCCP (mutant)<br /> | ||
| - | **[[1a6x]], [[3bdo]] – EcBCCP biotinyl domain – NMR<BR /> | ||
**[[2dn8]] – hBCCP2 residues 8-94 - NMR<BR /> | **[[2dn8]] – hBCCP2 residues 8-94 - NMR<BR /> | ||
**[[2kcc]] - hBCCP2 residues 891-964 – NMR<br /> | **[[2kcc]] - hBCCP2 residues 891-964 – NMR<br /> | ||
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**[[4hq6]] – hBCCP2 (mutant)<br /> | **[[4hq6]] – hBCCP2 (mutant)<br /> | ||
**[[2yl2]] – hBCCP1<br /> | **[[2yl2]] – hBCCP1<br /> | ||
| + | **[[1w93]] – yBCCP <br /> | ||
**[[2c00]] – BCCP – ''Pseudomonas aeruginosa''<br /> | **[[2c00]] – BCCP – ''Pseudomonas aeruginosa''<br /> | ||
| - | **[[1w93]] – yBCCP <br /> | ||
**[[2vpq]] – SaBCCP – ''Staphylococcus aureus''<br /> | **[[2vpq]] – SaBCCP – ''Staphylococcus aureus''<br /> | ||
| + | **[[1bnc]], [[1dv1]] - EcBCCP – ''Escherichia coli''<br /> | ||
| + | **[[2gps]], [[2gpw]], [[3g8d]] - EcBCCP (mutant)<br /> | ||
| + | **[[1a6x]], [[3bdo]] – EcBCCP biotinyl domain – NMR<BR /> | ||
* Biotin carboxyl carrier protein (BCCP) subunit complex | * Biotin carboxyl carrier protein (BCCP) subunit complex | ||
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**[[1bdo]] - EcBCCP + biotin <br /> | **[[1bdo]] - EcBCCP + biotin <br /> | ||
**[[2bdo]] - EcBCCP + biotin – NMR<br /> | **[[2bdo]] - EcBCCP + biotin – NMR<br /> | ||
| - | **[[1w96]] – yBCCP + soraphen <br /> | ||
| - | **[[3gid]], [[3jrx]] – hBCCP2 + soraphen <br /> | ||
**[[2j9g]] – EcBCCP + AMPPNP + ADP<br /> | **[[2j9g]] – EcBCCP + AMPPNP + ADP<br /> | ||
**[[1dv2]] – EcBCCP (mutant) + ATP<br /> | **[[1dv2]] – EcBCCP (mutant) + ATP<br /> | ||
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**[[3g8c]] - EcBCCP + biotin + bicarbonate + Mg + ADP<br /> | **[[3g8c]] - EcBCCP + biotin + bicarbonate + Mg + ADP<br /> | ||
**[[2vr1]] - EcBCCP + ATP analog<br /> | **[[2vr1]] - EcBCCP + ATP analog<br /> | ||
| + | **[[4hr7]] – EcBCCP + biotin carboxyl carrier protein<br /> | ||
**[[2vpq]] - SaBCCP + AMPPNP <br /> | **[[2vpq]] - SaBCCP + AMPPNP <br /> | ||
**[[2vqd]] - SaBCCP + AMPCP<br /> | **[[2vqd]] - SaBCCP + AMPCP<br /> | ||
**[[3ouz]] - CjBCCP + ADP – ''Campylobacter jejuni''<br /> | **[[3ouz]] - CjBCCP + ADP – ''Campylobacter jejuni''<br /> | ||
**[[3ouu]] - CjBCCP + b-g-ATP<br /> | **[[3ouu]] - CjBCCP + b-g-ATP<br /> | ||
| - | **[[4hr7]] – EcBCCP + biotin carboxyl carrier protein<br /> | ||
**[[4mv1]] – HiBCCP + Pi + ADP – ''Haemophilus influenzae''<br /> | **[[4mv1]] – HiBCCP + Pi + ADP – ''Haemophilus influenzae''<br /> | ||
**[[4mv3]] – HiBCCP + bicarbonate + AMPCP <br /> | **[[4mv3]] – HiBCCP + bicarbonate + AMPCP <br /> | ||
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* Biotin carboxyl carrier protein (BCCP) subunit complex with inhibitors | * Biotin carboxyl carrier protein (BCCP) subunit complex with inhibitors | ||
| - | **[[2v58]], [[2v59]], [[2v5a]] - EcBCCP + inhibitor<br /> | + | **[[3ff6]], [[5kkn]] – hBCCP2 + inhibitor <br /> |
| + | **[[3gid]], [[3jrx]] – hBCCP2 + soraphen <br /> | ||
| + | **[[1w96]] – yBCCP + soraphen <br /> | ||
| + | **[[3pgq]] - CjBCCP + pinoxaden<br /> | ||
| + | **[[2v58]], [[2v59]], [[2v5a]], [[6oi9]] - EcBCCP + inhibitor<br /> | ||
**[[2w6m]], [[2w6n]], [[2w6o]], [[2w6p]], [[2w6q]], [[2w6z]], [[2w70]], [[2w71]] - EcBCCP + fragment-based inhibitor<br /> | **[[2w6m]], [[2w6n]], [[2w6o]], [[2w6p]], [[2w6q]], [[2w6z]], [[2w70]], [[2w71]] - EcBCCP + fragment-based inhibitor<br /> | ||
**[[3jzf]], [[3jzi]] - EcBCCP + benzimidazole inhibitor<br /> | **[[3jzf]], [[3jzi]] - EcBCCP + benzimidazole inhibitor<br /> | ||
| - | **[[ | + | **[[6oi8]], [[6ojh]] - HiBCCP + inhibitor<br /> |
| - | + | ||
| - | + | ||
| - | + | ||
*Carboxyltransferase (CT) domain | *Carboxyltransferase (CT) domain | ||
| + | **[[3tdc]] - hCT2 residues 921-1676<br /> | ||
| + | **[[4asi]] - hCT1 residues 1493-2260<br /> | ||
| + | **[[2x24]] - CT + inhibitor – bovine<br /> | ||
**[[1uyt]], [[5i6e]] - yCT <BR /> | **[[1uyt]], [[5i6e]] - yCT <BR /> | ||
**[[1uyv]] - yCT (mutant) <BR /> | **[[1uyv]] - yCT (mutant) <BR /> | ||
| - | **[[2f9i]] - SaCT <BR /> | ||
| - | **[[2f9y]] - EcCT <BR /> | ||
| - | **[[5kdr]] - SaCT + moiramide <BR /> | ||
**[[1od2]] - yCT + adenine + acetyl CoA <BR /> | **[[1od2]] - yCT + adenine + acetyl CoA <BR /> | ||
**[[1od4]] - yCT + adenine<BR /> | **[[1od4]] - yCT + adenine<BR /> | ||
**[[1uyr]], [[1uys]], [[1w2x]], [[3k8x]], [[3h0j]], [[3h0s]], [[3h0q]], [[3pgq]], [[3tv5]], [[3tvu]], [[3tvw]], [[3tz3]], [[4wyo]], [[4wz8]], [[5ctb]], [[5ctc]], [[5cte]] - yCT + inhibitor<BR /> | **[[1uyr]], [[1uys]], [[1w2x]], [[3k8x]], [[3h0j]], [[3h0s]], [[3h0q]], [[3pgq]], [[3tv5]], [[3tvu]], [[3tvw]], [[3tz3]], [[4wyo]], [[4wz8]], [[5ctb]], [[5ctc]], [[5cte]] - yCT + inhibitor<BR /> | ||
| - | **[[ | + | **[[2f9i]] - SaCT <BR /> |
| - | **[[ | + | **[[5kdr]] - SaCT + moiramide <BR /> |
| - | **[[ | + | **[[2f9y]] - EcCT <BR /> |
*AC domains | *AC domains | ||
Current revision
3D structures of Acetyl-CoA carboxylase
Updated on 16-August-2022
