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6n00

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<StructureSection load='6n00' size='340' side='right'caption='[[6n00]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='6n00' size='340' side='right'caption='[[6n00]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6n00]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N00 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6N00 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6n00]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodopseudomonas_palustris_CGA009 Rhodopseudomonas palustris CGA009]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6N00 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6N00 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6mzz|6mzz]], [[6muy|6muy]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Haloacetate_dehalogenase Haloacetate dehalogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.8.1.3 3.8.1.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6n00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n00 OCA], [https://pdbe.org/6n00 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6n00 RCSB], [https://www.ebi.ac.uk/pdbsum/6n00 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6n00 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6n00 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6n00 OCA], [http://pdbe.org/6n00 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6n00 RCSB], [http://www.ebi.ac.uk/pdbsum/6n00 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6n00 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DEHA_RHOPA DEHA_RHOPA]] Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has lower activity towards bromoacetate and chloroacetate.<ref>PMID:21510690</ref> <ref>PMID:21510690</ref>
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[https://www.uniprot.org/uniprot/DEHA_RHOPA DEHA_RHOPA] Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has lower activity towards bromoacetate and chloroacetate.<ref>PMID:21510690</ref> <ref>PMID:21510690</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6n00" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6n00" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Dehalogenase 3D structures|Dehalogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Haloacetate dehalogenase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Besaw, J]]
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[[Category: Rhodopseudomonas palustris CGA009]]
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[[Category: Finke, A D]]
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[[Category: Besaw J]]
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[[Category: Gruner, S M]]
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[[Category: Finke AD]]
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[[Category: Mehrabi, P]]
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[[Category: Gruner SM]]
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[[Category: Miller, R J.D]]
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[[Category: Mehrabi P]]
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[[Category: Pare-Labrosse, O]]
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[[Category: Miller RJD]]
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[[Category: Sarrachini, A]]
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[[Category: Pare-Labrosse O]]
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[[Category: Wierman, J L]]
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[[Category: Sarrachini A]]
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[[Category: Defluorinase]]
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[[Category: Wierman JL]]
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[[Category: Dehalogenase]]
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[[Category: Hydrolase]]
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Current revision

Fluoroacetate dehalogenase, room temperature structure, using last 1 degree of total 3 degree oscillation and 144 kGy dose

PDB ID 6n00

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