3uqd

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<StructureSection load='3uqd' size='340' side='right'caption='[[3uqd]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
<StructureSection load='3uqd' size='340' side='right'caption='[[3uqd]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3uqd]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UQD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UQD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3uqd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UQD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UQD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=FBP:BETA-FRUCTOSE-1,6-DIPHOSPHATE'>FBP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.14&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3cqd|3cqd]], [[3n1c|3n1c]], [[3uqe|3uqe]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=FBP:BETA-FRUCTOSE-1,6-DIPHOSPHATE'>FBP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b1723, JW5280, PFK2, pfkB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uqd OCA], [https://pdbe.org/3uqd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uqd RCSB], [https://www.ebi.ac.uk/pdbsum/3uqd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uqd ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/6-phosphofructokinase 6-phosphofructokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.11 2.7.1.11] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uqd OCA], [http://pdbe.org/3uqd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3uqd RCSB], [http://www.ebi.ac.uk/pdbsum/3uqd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3uqd ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PFKB_ECOLI PFKB_ECOLI] Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.<ref>PMID:16866375</ref>
==See Also==
==See Also==
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*[[Phosphofructokinase (PFK)|Phosphofructokinase (PFK)]]
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*[[Phosphofructokinase 3D structures|Phosphofructokinase 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 6-phosphofructokinase]]
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[[Category: Escherichia coli K-12]]
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[[Category: Ecoli]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Babul, J]]
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[[Category: Babul J]]
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[[Category: Baez, M]]
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[[Category: Baez M]]
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[[Category: Cabrera, R]]
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[[Category: Cabrera R]]
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[[Category: Caniuguir, A]]
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[[Category: Caniuguir A]]
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[[Category: Pereira, H M]]
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[[Category: Pereira HM]]
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[[Category: Glycolysis]]
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[[Category: Pfk-2]]
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[[Category: Phosphofructokinase]]
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[[Category: Transferase]]
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Current revision

Crystal structure of the Phosphofructokinase-2 from Escherichia coli in complex with substrates and products

PDB ID 3uqd

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