2vko

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px <!-- The line below this paragraph, containing "STRUCTURE_2vko", creates the "Structure Box" on the page. You may change the PDB parameter (which sets the PD...)
Current revision (15:23, 13 December 2023) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2vko.jpg|left|200px]]
 
-
<!--
+
==Structure of the soluble domain of the membrane protein TM1634 from Thermotoga maritima==
-
The line below this paragraph, containing "STRUCTURE_2vko", creates the "Structure Box" on the page.
+
<StructureSection load='2vko' size='340' side='right'caption='[[2vko]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2vko]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VKO FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.79&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
-
{{STRUCTURE_2vko| PDB=2vko | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vko FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vko OCA], [https://pdbe.org/2vko PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vko RCSB], [https://www.ebi.ac.uk/pdbsum/2vko PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vko ProSAT]</span></td></tr>
-
 
+
</table>
-
'''STRUCTURE OF THE SOLUBLE DOMAIN OF THE MEMBRANE PROTEIN TM1634 FROM THERMOTOGA MARITIMA'''
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/Q9X1W9_THEMA Q9X1W9_THEMA]
-
 
+
<div style="background-color:#fffaf0;">
-
==Overview==
+
== Publication Abstract from PubMed ==
As a part of the Joint Center for Structural Genomics (JCSG) biological targets, the structures of soluble domains of membrane proteins from Thermotoga maritima were pursued. Here, we report the crystal structure of the soluble domain of TM1634, a putative membrane protein of 128 residues (15.1 kDa) and unknown function. The soluble domain of TM1634 is an alpha-helical dimer that contains a single tetratrico peptide repeat (TPR) motif in each monomer where each motif is similar to that found in Tom20. The overall fold, however, is unique and a DALI search does not identify similar folds beyond the 38-residue TPR motif. Two different putative ligand binding sites, in which PEG200 and Co(2+) were located, were identified using crystallography and NMR, respectively.
As a part of the Joint Center for Structural Genomics (JCSG) biological targets, the structures of soluble domains of membrane proteins from Thermotoga maritima were pursued. Here, we report the crystal structure of the soluble domain of TM1634, a putative membrane protein of 128 residues (15.1 kDa) and unknown function. The soluble domain of TM1634 is an alpha-helical dimer that contains a single tetratrico peptide repeat (TPR) motif in each monomer where each motif is similar to that found in Tom20. The overall fold, however, is unique and a DALI search does not identify similar folds beyond the 38-residue TPR motif. Two different putative ligand binding sites, in which PEG200 and Co(2+) were located, were identified using crystallography and NMR, respectively.
-
==About this Structure==
+
Structure and ligand binding of the soluble domain of a Thermotoga maritima membrane protein of unknown function TM1634.,McCleverty CJ, Columbus L, Kreusch A, Lesley SA Protein Sci. 2008 Mar 27;. PMID:18369189<ref>PMID:18369189</ref>
-
2VKO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VKO OCA].
+
-
==Reference==
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
Structure and ligand binding of the soluble domain of a Thermotoga maritima membrane protein of unknown function TM1634., McCleverty CJ, Columbus L, Kreusch A, Lesley SA, Protein Sci. 2008 Mar 27;. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18369189 18369189]
+
</div>
-
[[Category: Single protein]]
+
<div class="pdbe-citations 2vko" style="background-color:#fffaf0;"></div>
-
[[Category: Thermotoga maritima]]
+
== References ==
-
[[Category: Columbus, L.]]
+
<references/>
-
[[Category: Jcsg, Joint Center for Structural Genomics.]]
+
__TOC__
-
[[Category: Kreusch, A.]]
+
</StructureSection>
-
[[Category: Lesley, S A.]]
+
[[Category: Large Structures]]
-
[[Category: Mccleverty, C J.]]
+
-
[[Category: Jcsg]]
+
-
[[Category: Joint center for structural genomic]]
+
-
[[Category: Membrane protein]]
+
-
[[Category: Sad]]
+
-
[[Category: Structural genomic]]
+
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
-
[[Category: Tpr motif]]
+
[[Category: Columbus L]]
 +
[[Category: Kreusch A]]
 +
[[Category: Lesley SA]]
 +
[[Category: McCleverty CJ]]

Current revision

Structure of the soluble domain of the membrane protein TM1634 from Thermotoga maritima

PDB ID 2vko

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2vko"
Personal tools