5qmt

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'''Unreleased structure'''
 
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The entry 5qmt is ON HOLD until Paper Publication
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==Group deposition of library data - Crystal Structure of EcDsbA after initial refinement with no ligand modelled (structure G10_1)==
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<StructureSection load='5qmt' size='340' side='right'caption='[[5qmt]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
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Authors: Ilyichova, O.V., Bentley, M.R., Doak, B.C., Scanlon, M.J.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5qmt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QMT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QMT FirstGlance]. <br>
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Description: Group deposition of library data -Crystal Structure of EcDsbA after initial refinement with no ligand modelled (structure G10_1)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.043&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qmt OCA], [https://pdbe.org/5qmt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qmt RCSB], [https://www.ebi.ac.uk/pdbsum/5qmt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qmt ProSAT]</span></td></tr>
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[[Category: Doak, B.C]]
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</table>
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[[Category: Ilyichova, O.V]]
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== Function ==
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[[Category: Scanlon, M.J]]
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[https://www.uniprot.org/uniprot/DSBA_ECOLI DSBA_ECOLI] Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbA is reoxidized by DsbB. Required for pilus biogenesis. PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing (deletion of dsbA/dsbB, treatment with dithiothreitol). MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.<ref>PMID:1429594</ref> <ref>PMID:22267510</ref>
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[[Category: Bentley, M.R]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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[[Category: Bentley MR]]
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[[Category: Doak BC]]
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[[Category: Ilyichova OV]]
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[[Category: Scanlon MJ]]

Current revision

Group deposition of library data - Crystal Structure of EcDsbA after initial refinement with no ligand modelled (structure G10_1)

PDB ID 5qmt

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