4nph

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<StructureSection load='4nph' size='340' side='right'caption='[[4nph]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
<StructureSection load='4nph' size='340' side='right'caption='[[4nph]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4nph]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NPH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NPH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4nph]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NPH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NPH FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ssaN, STM1415 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 SALTY])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/H(+)-transporting_two-sector_ATPase H(+)-transporting two-sector ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nph OCA], [https://pdbe.org/4nph PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nph RCSB], [https://www.ebi.ac.uk/pdbsum/4nph PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nph ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nph OCA], [http://pdbe.org/4nph PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nph RCSB], [http://www.ebi.ac.uk/pdbsum/4nph PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nph ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SCTN2_SALTY SCTN2_SALTY] ATPase component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:24722491). Acts as a molecular motor to provide the energy that is required for the export of proteins (By similarity). Required for type III secretion apparatus (T3SA) formation, secretion of a subset of SPI-2 effectors and virulence (PubMed:24722491, PubMed:25035427). May play a critical role in T3SS substrate recognition, disassembly of the effector/chaperone complex and unfolding of the effector in an ATP-dependent manner prior to secretion (Probable). Releases the effector protein SseB from the T3SS-2 specific chaperone SsaE in an ATP-dependent manner (PubMed:24722491).[UniProtKB:P0A1B9]<ref>PMID:24722491</ref> <ref>PMID:25035427</ref> <ref>PMID:24722491</ref> <ref>PMID:25035427</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Salty]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Coombes, B K]]
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[[Category: Coombes BK]]
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[[Category: Cooper, C A]]
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[[Category: Cooper CA]]
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[[Category: Junop, M S]]
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[[Category: Junop MS]]
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[[Category: Sugiman-Marangos, S N]]
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[[Category: Sugiman-Marangos SN]]
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[[Category: Zhang, K]]
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[[Category: Zhang K]]
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[[Category: Atpase]]
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[[Category: Protein transport]]
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[[Category: T3ss]]
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Current revision

Crystal structure of SsaN from Salmonella enterica

PDB ID 4nph

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OCA

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