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4mzp

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<StructureSection load='4mzp' size='340' side='right'caption='[[4mzp]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='4mzp' size='340' side='right'caption='[[4mzp]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4mzp]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Staan Staan]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MZP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MZP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4mzp]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_N315 Staphylococcus aureus subsp. aureus N315]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MZP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MZP FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mzm|4mzm]], [[4mzt|4mzt]], [[2mf2|2mf2]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.702&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mazF, SA1873 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158879 STAAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mzp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mzp OCA], [https://pdbe.org/4mzp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mzp RCSB], [https://www.ebi.ac.uk/pdbsum/4mzp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mzp ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mzp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mzp OCA], [http://pdbe.org/4mzp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mzp RCSB], [http://www.ebi.ac.uk/pdbsum/4mzp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mzp ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MAZF_STAAN MAZF_STAAN]] Toxic component of a toxin-antitoxin (TA) module. Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. Cleavages occur preferentially in a U-rich region with a consensus sequence of 5'-[ACG]UU[ACG]-3' in single-stranded RNA (By similarity).
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[https://www.uniprot.org/uniprot/MAZF_STAAN MAZF_STAAN] Toxic component of a toxin-antitoxin (TA) module. Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. Cleavages occur preferentially in a U-rich region with a consensus sequence of 5'-[ACG]UU[ACG]-3' in single-stranded RNA (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Staan]]
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[[Category: Staphylococcus aureus subsp. aureus N315]]
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[[Category: Cheung, A]]
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[[Category: Cheung A]]
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[[Category: Loris, R]]
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[[Category: Loris R]]
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[[Category: Nuland, N A.J van]]
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[[Category: Zorzini V]]
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[[Category: Zorzini, V]]
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[[Category: Van Nuland NAJ]]
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[[Category: Ccdb/mazf fold]]
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[[Category: Hydrolase]]
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[[Category: Maze]]
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[[Category: Mrna interferase]]
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[[Category: Ribonuclease]]
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Current revision

MazF from S. aureus crystal form III, C2221, 2.7 A

PDB ID 4mzp

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