This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4mui

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (16:42, 20 September 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 3: Line 3:
<StructureSection load='4mui' size='340' side='right'caption='[[4mui]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='4mui' size='340' side='right'caption='[[4mui]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4mui]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MUI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MUI FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4mui]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MUI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MUI FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2DQ:(5-METHOXY-2-{[(4-METHOXYPHENYL)SULFONYL]CARBAMOYL}-1H-INDOL-1-YL)ACETIC+ACID'>2DQ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mq6|4mq6]], [[4mue|4mue]], [[4muf|4muf]], [[4mug|4mug]], [[4muh|4muh]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2DQ:(5-METHOXY-2-{[(4-METHOXYPHENYL)SULFONYL]CARBAMOYL}-1H-INDOL-1-YL)ACETIC+ACID'>2DQ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT3707, MTCY07H7B.20, panC, Rv3602c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mui OCA], [https://pdbe.org/4mui PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mui RCSB], [https://www.ebi.ac.uk/pdbsum/4mui PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mui ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantoate--beta-alanine_ligase Pantoate--beta-alanine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.1 6.3.2.1] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mui OCA], [http://pdbe.org/4mui PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mui RCSB], [http://www.ebi.ac.uk/pdbsum/4mui PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mui ProSAT]</span></td></tr>
+
</table>
</table>
-
== Function ==
 
-
[[http://www.uniprot.org/uniprot/PANC_MYCTU PANC_MYCTU]] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<ref>PMID:11669627</ref>
 
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 29: Line 25:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Pantoate--beta-alanine ligase]]
+
[[Category: Mycobacterium tuberculosis]]
-
[[Category: Blundell, T L]]
+
[[Category: Blundell TL]]
-
[[Category: Silvestre, H L]]
+
[[Category: Silvestre HL]]
-
[[Category: Atp binding]]
+
-
[[Category: Ligase-ligase inhibitor complex]]
+
-
[[Category: Pantoate-ligase]]
+

Current revision

Crystal structure of pantothenate synthetase in complex with 2-(5-methoxy-2-(4-methoxyphenylsulfonylcarbamoyl)-1H-indol-1-yl)acetic acid

PDB ID 4mui

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4mui"
Personal tools