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4mro
From Proteopedia
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<StructureSection load='4mro' size='340' side='right'caption='[[4mro]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='4mro' size='340' side='right'caption='[[4mro]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4mro]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4mro]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MRO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MRO FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MG0:2-(4-{4-[(6-AMINOPYRIDIN-3-YL)SULFONYL]PIPERAZIN-1-YL}PHENYL)-1,1,1,3,3,3-HEXAFLUOROPROPAN-2-OL'>MG0</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=MG0:2-(4-{4-[(6-AMINOPYRIDIN-3-YL)SULFONYL]PIPERAZIN-1-YL}PHENYL)-1,1,1,3,3,3-HEXAFLUOROPROPAN-2-OL'>MG0</scene>, <scene name='pdbligand=S6P:D-SORBITOL-6-PHOSPHATE'>S6P</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mro FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mro OCA], [https://pdbe.org/4mro PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mro RCSB], [https://www.ebi.ac.uk/pdbsum/4mro PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mro ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/GCKR_HUMAN GCKR_HUMAN] Inhibits glucokinase by forming an inactive complex with this enzyme. |
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==See Also== | ==See Also== | ||
*[[Glucokinase Regulatory Protein|Glucokinase Regulatory Protein]] | *[[Glucokinase Regulatory Protein|Glucokinase Regulatory Protein]] | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Ashton | + | [[Category: Ashton KS]] |
| - | [[Category: Bartberger | + | [[Category: Bartberger MD]] |
| - | [[Category: Chen | + | [[Category: Chen J]] |
| - | [[Category: Chmait | + | [[Category: Chmait S]] |
| - | [[Category: Cupples | + | [[Category: Cupples R]] |
| - | [[Category: Fotsch | + | [[Category: Fotsch C]] |
| - | [[Category: Galbreath | + | [[Category: Galbreath E]] |
| - | [[Category: Hale | + | [[Category: Hale C]] |
| - | [[Category: Helmering | + | [[Category: Helmering J]] |
| - | + | [[Category: Jordan SR]] | |
| - | [[Category: Jordan | + | [[Category: Kunz K]] |
| - | [[Category: Kunz | + | [[Category: LLoyd DJ]] |
| - | [[Category: LLoyd | + | [[Category: Liu L]] |
| - | [[Category: Liu | + | [[Category: Michelsen K]] |
| - | [[Category: Michelsen | + | [[Category: Nishimura N]] |
| - | [[Category: Nishimura | + | [[Category: Norman MH]] |
| - | [[Category: Norman | + | [[Category: Pennington LD]] |
| - | [[Category: Pennington | + | [[Category: Poon SF]] |
| - | [[Category: Poon | + | [[Category: Sivits G]] |
| - | [[Category: Sivits | + | [[Category: St Jean DJ]] |
| - | [[Category: Stec | + | [[Category: Stec MM]] |
| - | [[Category: Tamayo | + | [[Category: Tamayo N]] |
| - | [[Category: Van | + | [[Category: Van G]] |
| - | [[Category: Yang | + | [[Category: Yang K]] |
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Current revision
Human GKRP bound to AMG-5980 and S6P
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Categories: Homo sapiens | Large Structures | Ashton KS | Bartberger MD | Chen J | Chmait S | Cupples R | Fotsch C | Galbreath E | Hale C | Helmering J | Jordan SR | Kunz K | LLoyd DJ | Liu L | Michelsen K | Nishimura N | Norman MH | Pennington LD | Poon SF | Sivits G | St Jean DJ | Stec MM | Tamayo N | Van G | Yang K
