4mul
From Proteopedia
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<StructureSection load='4mul' size='340' side='right'caption='[[4mul]], [[Resolution|resolution]] 1.75Å' scene=''> | <StructureSection load='4mul' size='340' side='right'caption='[[4mul]], [[Resolution|resolution]] 1.75Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[4mul]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4mul]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MUL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MUL FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2DW:{5-METHOXY-2-[(NAPHTHALEN-2-YLSULFONYL)CARBAMOYL]-1H-INDOL-1-YL}ACETIC+ACID'>2DW</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2DW:{5-METHOXY-2-[(NAPHTHALEN-2-YLSULFONYL)CARBAMOYL]-1H-INDOL-1-YL}ACETIC+ACID'>2DW</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mul FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mul OCA], [https://pdbe.org/4mul PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mul RCSB], [https://www.ebi.ac.uk/pdbsum/4mul PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mul ProSAT]</span></td></tr> | |
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- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
- | == Function == | ||
- | [[http://www.uniprot.org/uniprot/PANC_MYCTU PANC_MYCTU]] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<ref>PMID:11669627</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: | + | [[Category: Mycobacterium tuberculosis]] |
- | [[Category: Blundell | + | [[Category: Blundell TL]] |
- | [[Category: Silvestre | + | [[Category: Silvestre HL]] |
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Current revision
Crystal structure of pantothenate synthetase in complex with 2-(5-methoxy-2-(naphthalen-2-ylsulfonylcarbamoyl)-1H-indol-1-yl)acetic acid
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