4oj2

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<StructureSection load='4oj2' size='340' side='right'caption='[[4oj2]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
<StructureSection load='4oj2' size='340' side='right'caption='[[4oj2]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4oj2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OJ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OJ2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4oj2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OJ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OJ2 FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AQP2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.05&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oj2 OCA], [http://pdbe.org/4oj2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4oj2 RCSB], [http://www.ebi.ac.uk/pdbsum/4oj2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4oj2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4oj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oj2 OCA], [https://pdbe.org/4oj2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oj2 RCSB], [https://www.ebi.ac.uk/pdbsum/4oj2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oj2 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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[[http://www.uniprot.org/uniprot/AQP2_HUMAN AQP2_HUMAN]] Nephrogenic diabetes insipidus. The disease is caused by mutations affecting the gene represented in this entry.
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[https://www.uniprot.org/uniprot/AQP2_HUMAN AQP2_HUMAN] Nephrogenic diabetes insipidus. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/AQP2_HUMAN AQP2_HUMAN]] Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
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[https://www.uniprot.org/uniprot/AQP2_HUMAN AQP2_HUMAN] Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Engel, A]]
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[[Category: Engel A]]
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[[Category: Lodowski, D]]
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[[Category: Lodowski D]]
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[[Category: TEMIMPS, Transcontinental EM Initiative for Membrane Protein Structure]]
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[[Category: Vahedi-Faridi A]]
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[[Category: Vahedi-Faridi, A]]
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[[Category: Aquaporin-2]]
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[[Category: C-terminal alpha helix]]
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[[Category: Membrane]]
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[[Category: Npa motif]]
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[[Category: PSI, Protein structure initiative]]
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[[Category: Psi-biology]]
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[[Category: Structural genomic]]
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[[Category: Temimp]]
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[[Category: Transcontinental em initiative for membrane protein structure]]
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[[Category: Transport protein]]
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[[Category: Water channel]]
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[[Category: Water transport simulation]]
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Current revision

The structure of aquaporin

PDB ID 4oj2

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