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Calcineurin

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== Function ==
== Function ==
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'''Calcineurin''' (CN) is a eukaryotic calcium-dependent serine/threonine protein phosphatase 2B which dephosphorylates serine/threonine residues. CN activates T cells of the immune system. It participates in Ca+2-dependent signal transduction pathways.
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'''Calcineurin''' (CN) is a eukaryotic calcium-dependent '''serine/threonine protein phosphatase 2B''' which dephosphorylates serine/threonine residues. CN activates T cells of the immune system. It participates in Ca+2-dependent signal transduction pathways.
For more details see [[Group:MUZIC:Calcineurin]].
For more details see [[Group:MUZIC:Calcineurin]].

Current revision

Human calcineurin regulatory subunit B (magenta) and catalytic subunit A (cyan) complex with Ca+2 (green), Fe +3 (orange) and Zn+2 (grey) ions, 1aui

Drag the structure with the mouse to rotate

References

  1. ↑ Kissinger CR, Parge HE, Knighton DR, Lewis CT, Pelletier LA, Tempczyk A, Kalish VJ, Tucker KD, Showalter RE, Moomaw EW, et al.. Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex. Nature. 1995 Dec 7;378(6557):641-4. PMID:8524402 doi:http://dx.doi.org/10.1038/378641a0

See Group:MUZIC:Calcineurin.

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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