6jv2

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "6jv2" [edit=sysop:move=sysop])
Current revision (10:39, 27 March 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 6jv2 is ON HOLD
+
==Structure of RyR2 (P/L-Ca2+/Ca2+-CaM dataset)==
 +
<SX load='6jv2' size='340' side='right' viewer='molstar' caption='[[6jv2]], [[Resolution|resolution]] 4.40&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[6jv2]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JV2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JV2 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.4&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jv2 OCA], [https://pdbe.org/6jv2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jv2 RCSB], [https://www.ebi.ac.uk/pdbsum/6jv2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jv2 ProSAT]</span></td></tr>
 +
</table>
 +
== Disease ==
 +
[https://www.uniprot.org/uniprot/CALM1_HUMAN CALM1_HUMAN] The disease is caused by mutations affecting the gene represented in this entry. Mutations in CALM1 are the cause of CPVT4. The disease is caused by mutations affecting the gene represented in this entry. Mutations in CALM1 are the cause of LQT14.
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CALM1_HUMAN CALM1_HUMAN] Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (PubMed:16760425). Mediates calcium-dependent inactivation of CACNA1C (PubMed:26969752). Positively regulates calcium-activated potassium channel activity of KCNN2 (PubMed:27165696).<ref>PMID:16760425</ref> <ref>PMID:23893133</ref> <ref>PMID:26969752</ref> <ref>PMID:27165696</ref>
-
Authors:
+
==See Also==
-
 
+
*[[Calmodulin 3D structures|Calmodulin 3D structures]]
-
Description:
+
== References ==
-
[[Category: Unreleased Structures]]
+
<references/>
 +
__TOC__
 +
</SX>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Sus scrofa]]
 +
[[Category: Chi XM]]
 +
[[Category: Gong DS]]
 +
[[Category: Huang GXY]]
 +
[[Category: Lei JL]]
 +
[[Category: Yan N]]
 +
[[Category: Zhou GW]]

Current revision

Structure of RyR2 (P/L-Ca2+/Ca2+-CaM dataset)

6jv2, resolution 4.40Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6jv2"
Personal tools