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4qoi
From Proteopedia
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<StructureSection load='4qoi' size='340' side='right'caption='[[4qoi]], [[Resolution|resolution]] 1.55Å' scene=''> | <StructureSection load='4qoi' size='340' side='right'caption='[[4qoi]], [[Resolution|resolution]] 1.55Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4qoi]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4qoi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QOI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QOI FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=ML1:N-[2-(5-METHOXY-1H-INDOL-3-YL)ETHYL]ACETAMIDE'>ML1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qoi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qoi OCA], [https://pdbe.org/4qoi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qoi RCSB], [https://www.ebi.ac.uk/pdbsum/4qoi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qoi ProSAT]</span></td></tr> | |
| - | < | + | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/NQO2_HUMAN NQO2_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.<ref>PMID:18254726</ref> |
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| + | ==See Also== | ||
| + | *[[Quinone reductase|Quinone reductase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Antoine | + | [[Category: Antoine M]] |
| - | [[Category: Boutin | + | [[Category: Boutin JA]] |
| - | [[Category: Ferry | + | [[Category: Ferry G]] |
| - | [[Category: Isabet | + | [[Category: Isabet T]] |
| - | [[Category: Serriere | + | [[Category: Serriere J]] |
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Current revision
Crystal structure of FMN quinone reductase 2 in complex with melatonin at 1.55A
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